Sentences with word «pellagra»

The U.S. Public Health and Marine Hospital Service — soon to be known as the Public Health Service (PHS), a precursor to the National Institutes of Health — began studying pellagra in 1909.

Lysine deficiency can result in vitamin B3 (niacin) deficiency and this can cause a disease called pellagra [7].

Vitamin B3 deficiency lasting for few months [7] causes pellagra (Italian pella agra = rough skin) with «four D» symptoms: dermatitis with burn - like blisters and later rough, scaly and painful, but not itchy, lesions on the sun - exposed areas (face, extension side of the hands / arms and leg / feet), diarrhea, dementia and death (if not treated)[1].

Right away, Goldberger saw a flaw in the fly - infection theory: Institutions with pellagra cases consistently reported that staff members, presumably vulnerable to the same flies, weren't diagnosed with the disease.

It also acts as an acid, chelating the vitamin niacin, which is basic, causing the condition known as pellagra.

Visions of bare foot illiterate upstate New Yorkers, dressed in flour sacks and ravaged by pellagra, must have danced in the audience's collective head.

Goldberger died in 1929, the same year that pellagra cases at large started declining.

No one got pellagra.

His next quest: to induce pellagra in healthy subjects.

Wan na go to the dollar dance at a Bugtussle wedding, but don't have a cousin named Cletis with a recessive pellagra gene?

Why not pellagra?

In 1914, he assigned the PHS pellagra studies to Joseph Goldberger.

The potential for a widespread pellagra outbreak surged in flood - ravaged areas of Tennessee, Arkansas, Louisiana and Mississippi.

The P - P Factor Goldberger focused on identifying the missing dietary element, which he called the P - P factor, for pellagra preventive.

Repeated testing on the dogs, then on human subjects, confirmed that brewer's yeast, a product the poor could afford, contained the P - P factor that cured and prevented pellagra.

Without the yeast, the dogs developed pellagra.

Yet pellagra raged on, propelled by plummeting cotton prices in 1920.

He also organized extensive epidemiological studies of seven villages that conclusively proved the link between pellagra and poverty.

People with pellagra experienced horrible rashes, diarrhea and dementia.

[10] Chronic alcoholism can also cause poor absorption which combines with a diet already low in niacin and tryptophan to produce pellagra.

[51] It was estimated that there were 3 million cases and 100,000 deaths due to pellagra during the epidemic.

Sufferers of pellagra get a thick, scaly skin rash on exposure to sunlight, but they also get depression, disorientation, and apathy.

Some of the symptoms she saw in both the mothers and surviving pups resembled those of a debilitating disease called pellagra.

A deficiency of niacin, or vitamin 83, causes pellagra, with its associated skin breakdown.

These diets led to diseases such as black tongue (pellagra in humans), rickets, and other less commonly known ailments, many of them fatal.

A deficiency of vitamin B3 results in the skin condition known as pellagra; therefore, healthy skin depends on obtaining adequate levels of this nutrient.

A critical review: A reexamination of the composition of diets associated with pellagra.

Wheat and oats induce rickets [13] while corn induces pellagra.

Many of them have one of the diseases of chronic alcoholism — polyneuropathy, pellagra, cirrhosis of the liver, or others.

Psychoses due to syphilis, pellagra, and lead poisoning have been practically eliminated through medical progress.

They include polyneuropathy, pellagra, cirrhosis of the liver, Korsakoff's psychosis, delirium tremens, acute alcoholic hallucinosis, and others.

The rest of upstate will get an influx of poverty warriors from Manhattan (take that, pellagra) and taxpayer jacked downtown development that smacks of Governor George Pataki.

Not just because of the pellagra.

One theory held that pellagra was an infectious disease carried by Simulium flies.

The recent identification of diseases caused by dietary deficiencies further convinced Goldberger that a corn - based diet could be pellagra's cause.

Niacin has since become a dietary staple, now better known for fighting high cholesterol than pellagra.

In the intervening centuries, pellagra was particularly widespread — and well documented — in northern Italy, with cases reported as far afield as South Africa and Egypt.

He tried to infect himself, his wife and other volunteers with pellagra by injecting and ingesting the skin scales, urine, feces, blood and saliva from pellagra patients.

In 1907, physicians at two Southern mental institutions began to suspect their patients» symptoms were the result of pellagra, Italian for «rough or dry skin.»

Today, pellagra is mostly relegated to history lessons and medical reference books.

One of the first doctors who made the connection to pellagra was James Babcock of the South Carolina State Hospital for the Insane.

In 1922, he tried to induce black - tongue disease — the canine analog of pellagra — in his laboratory dogs by feeding them a diet typical of poor Southerners, plus brewer's yeast purely to stimulate the dogs» appetite.

He went on to organize the first U.S. conferences on pellagra, where two competing theories on the disease's cause went head to head.

Goldberger was convinced he had proven the link between the Southern poverty diet and pellagra.

They may be suffering from something similar to the human disease pellagra.

A number of diseases caused by nutrient deficiency, such as scurvy, beriberi, pellagra, and pernicious anemia, display psychiatric symptoms like irritability and depression.