Sentences with phrase «penetrance susceptibility»

The more cases there are then the more likely it is that there is a high penetrance susceptibility gene in the family as described above.

Deciphering the genetic architecture of low - penetrance susceptibility to colorectal cancer.

Genetic Diagnosis of High - Penetrance Susceptibility for Colorectal Cancer (CRC) Is Achievable for a High Proportion of Familial CRC by Exome Sequencing.

Not exact matches

In the majority of families with high penetrance melanoma susceptibility genes however the family history will reveal melanoma predominantly.

For melanoma it is easiest to group susceptibility genes into rare high penetrance genes and more common lower penetrance genes but the truth is that this distinction is not absolute.

The first paper was published in 2009, and a series of more recent papers have shown increased numbers of these low penetrance melanoma susceptibility genes.

Project Title: Using functional studies to explore potential high penetrance melanoma susceptibility genes identified using whole exome and genome sequencing.

There are other possible low penetrance genes promoting susceptibility to melanoma which Melanoma Genetics Consortium and others are exploring.