Sentences with word «pentose»

uantitation of metabolites associated primarily with glycolysis, TCA cycle, and pentose phosphate pathway.
D - ribose is a natural pentose sugar that is designed for the support of cardiovascular health, fatigue, energy production, and mitochondrial function †.
By painstakingly analyzing long lists of metabolites, McDonald and Vanderbilt undergraduate student Anna Word discovered that distant metastases altered their metabolism by consuming excess amounts of glucose and directing it through the pentose phosphate metabolic pathway.
They also found that distant metastases and their precursors processed glucose through a growth - promoting series of metabolic reactions called the pentose phosphate pathway, which burns (or oxidizes) glucose - derived molecules into building blocks for tumors.
Feinberg adds that the groups are also trying to learn how activation of the pentose phosphate pathway leads to the massive epigenetic changes seen.
To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the researchers had detected in distant metastases, they treated tumor cells from different sites in a single patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not used in humans because of its severe side effects.
«We still don't know how the pentose phosphate pathway gets turned on, for example,» says McDonald, «but we're working on figuring it out.»
He was well know for his contributions to elucidating the pentose phosphate pathway.
The pentose phosphate pathway as a target for cardiac maturation is covered by a provisional patent application filed by the UCLA Technology Development Group on behalf of the University of California Regents, with Austin Nakano and Haruko Nakano, a UCLA assistant researcher, as inventors.
The researchers discovered that, when exposed to extra glucose, the cardiomyocytes over-activated the pentose phosphate pathway — a cellular process that, among other things, generates nucleotides, the building blocks of DNA.
Today, most protocols for generating cardiomyocytes in the lab lead to immature cells, but targeting the pentose phosphate pathway could help generate more mature cells for regenerating heart cells or for research purposes.
In cells with high glucose levels, the pentose phosphate pathway made more nucleotides than usual.
Activation of mTORC1 induces genes involved in glycolysis, the pentose phosphate pathway, and sterol and lipid biosynthesis (52).
Administration of exogenous ribose bypasses the rate - limiting steps in the pentose phosphate pathway, resulting in a significant acceleration of PRPP.
Ribose is formed naturally via the pentose phosphate pathway.
The pentoses in hemicellulose are usually D - sugar isomers, but it may contain some L - sugars.
The pentose phosphate pathway is something I first learned the practical application for from reading body by science by Dr Doug McGuff.
[78] All amino acids are synthesized from intermediates in glycolysis, the citric acid cycle, or the pentose phosphate pathway.
So could low levels of the NADPH from the pentose phosphate pathway lead to low levels of cortisol?
And speaking of the pentose phosphate pathway, by the way, in order to make steroid hormones, you have to have NADPH.
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