Sentences with phrase «peptide fibril»

Structural model of Alzheimer Amyloid A-beta 1 - 42 peptide fibril derived from an experimental structure (PDB: 2MXU).

This A-beta peptide fibril has been rendered in 3 - D by a transmission electron microscope, providing the most detailed look yet at the telltale sign of Alzheimer's disease.

It has been demonstrated that silk properties (in terms of different reeling methods [32], [42], environmental conditions [8], [20], types of silk [e.g. dragline, viscid or egg sac silk][22], [24], [34]-RRB- are species - specific and lead to silk - based peptide fibrils or protein aggregates with different structural and mechanical properties.

Not exact matches

The platform builds the fibrils by combining the properties of the nanotube with a synthetic peptide fragment that is placed inside the cylinder.

This peptide, 39 to 42 amino acids long, is toxic to nerve cells and is able to form elongated fibrils.

A European research team and a team from the United States (Massachussetts Institute of Technology in cooperation with Lund University) have simultaneously succeeded in elucidating the structure of the most disease - relevant beta - amyloid peptide 1 - 42 fibrils at atomic resolution.

Many peptides and proteins have an innate ability to assemble into long, slender fibers called fibrils and other shapes.

Four of the mAbs, 2T5C9, 2G9C, T1F11, and TB2H7, demonstrated diagnostic potential in enzyme - linked immunosorbent assays (ELISA) by their low to sub-nanomolar cross-reactivity with recombinant wild - type (WT) and mutant TTR aggregates and lack of binding to native TTR or amyloid fibrils formed by other peptides or proteins.

This toxicity is mediated by the fibrillar form of the amylin peptide and requires direct contact of the fibrils with the cell surface.