Sentences with phrase «peptide nucleic»

Led by Dr. Peter Glazer, chair of therapeutic radiology, Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used synthetic molecules similar to DNA — called peptide nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.

In addition to Orgel and Ghadiri, authors on the paper, entitled «Self - Assembling Sequence - Adaptive Peptide Nucleic Acids,» are Yasuvuki Ura, John Beierle, and Luke Leman, all from The Scripps Research Institute.

Thioester bonds reversibly with the cysteine on the peptides to form thioester peptide nucleic acid (tPNA).

A peptide nucleic acid - nuclear localization signal fusion that mediates nuclear transport of DNA.

Peptide nucleic acid, a synthetic hybrid of protein and DNA, could form the basis of a new class of drugs — and of artificial life unlike anything found in nature

Led by Dr. Peter Glazer, chair of therapeutic radiology, Dr. Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used synthetic molecules similar to DNA — called peptide nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.

Not exact matches

The probablility of all the cellular machinery (enzymes, ion channels, RNA polymerase, anabolic and catabolic pathways, etc) just assembling out of randomn peptides and nucleic acids is infinitely small.

Life on Earth originated in an intimate partnership between the nucleic acids (genetic instructions for all organisms) and small proteins called peptides, according to two new papers from biochemists and biologists at the University of North Carolina at Chapel Hill and the University of Auckland.

«These interdependent peptides and the nucleic acids encoding them would have been able to assist each other's molecular self - organization despite the continual random disruptions that beset all molecular processes,» Carter said.

«There is something very special about peptides, nucleic acids, polysaccharides and lipids and their ability to work together to do something they couldn't have done separately,» he said.

[6] Bioplex technology: Novel synthetic gene delivery system based on peptides anchored to nucleic acids.

He has been actively involved in the discovery of several nucleic acid and peptide drug leads that were progressed into clinical studies.

Jörg brings over 17 years» experience in drug discovery and development across key areas such as oncology, infectious diseases, vaccinology, and autoimmunity, with a focus on peptide and nucleic acid - based therapeutics.

«So it is tantalizing to think about the possibility of peptides and nucleic acids involved in primordial genetic systems,» says Ghadiri.