Sentences with phrase «peptide sequence by»

Not exact matches

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that has been linked to toxic aggregates of poly - Gly - Ala (poly - GA) peptides generated by aberrant translation of an expanded nucleotide repeat sequence.

An article on the research, «Purification of Synthetic Peptides Using a Catching Full - Length Sequence by Polymerization Approach,» coauthored by Fang, postdoctoral fellow Mingcui Zhang and graduate student Durga Pokharel, was published online in the journal Organic Letters.

Sun decided to study a fraction of the peptide sequence that gave the glue its adhesive ability by attaching a heterogeneous hydrophilic peptide segment inspired by spider silk proteins.

With no candidate targets, the team took an objective approach by applying a peptide phage library to MDSCs, which permitted mass screening for candidate peptides — short sequences of amino acids — that bind to the surface of the MDSCs.

By allowing these peptides — strings of polymers composed of amino acids — to continuously reorganize their sequences, they will eventually form those polymers that are most suited to the environment at the expense of less favored structures.

As part of this research, «we identified highly conserved unique protein sequences that were predicted by computer modeling to assume structures characteristic of natural antibacterial peptides.

Our findings are in agreement with a recently published study by Oskarsson et al. (2015) in which Tg mice injected through the tail vein with in vitro — generated aggregates from synthetic peptides containing the sequence of IAPP developed a higher percentage of IAPP aggregates in the pancreas than did untreated controls when subjected to a high - fat diet.

A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma.

Prior to the new study, scientists thought that the machinery in a cell created signalling peptides by cutting fragments out of proteins in sequence, and displaying these in order on the surface of the cell.

Peptide quantification is facilitated by associating signal intensities in features with peptide sequences derived from MS2 sPeptide quantification is facilitated by associating signal intensities in features with peptide sequences derived from MS2 speptide sequences derived from MS2 spectra.

Briefly, trastuzumab heavy and light chain sequences were amplified with PCR and a truncated FMDV 2A peptide sequence was inserted between them by splice overlap extension.

Protein coding sequences were flanked with unique NotI and AscI restriction sites and subcloned into a derivative of the pTT3 expression plasmid between a 5» mouse variable κ light chain signal peptide [32], and a 3» tag consisting of the rat Cd4 domains 3 and 4 followed by an enzymatic biotinylation sequence and a hexahistidine tag [33].