Not exact matches
Gene expression profiling was
performed on blood samples taken from 70 RA patients: 50 of whom had shown a good response to the anti-TNF biologic treatment adalimumab, 20 of whom had shown no response to this drug.
The TGen team
performed deep genomic
profiling, integrating
gene copy number,
gene expression and DNA methylation datasets on a collection of 35 breast - brain metastases samples.
Scientists
performed an integrative transcriptomic analysis, comparing
gene expression networks across all three groups of participants and finding unique molecular
profiles and pathway enrichment patterns.
Resident macrophages from the same lineage, such as liver Kupffer cells, brain microglia, epidermal Langerhans cells, lung alveolar macrophages..., display tissue - specific phenotypes,
perform tissue - specific functions and have distinct
gene expression profiles.
In order to build a tissue similarity matrix of the correlation
profiles (
gene expression and PMI) we
performed a pairwise comparison of all tissues.