Sentences with phrase «performing genetic studies»

Performing genetic studies in multiple human populations can identify disease risk alleles that are common in one population but rare in others, with the potential to illuminate pathophysiology, health disparities, and the population genetic origins of disease alleles.

In anticipation of targeted medicines, pharmaceutical and biotechnology companies are increasingly performing genetic studies of clinical trial participants in hopes of identifying genetic profiles that predict therapeutic outcomes.

Not exact matches

Whilst there I worked on a research project studying the genetics of inherited deafness and also performed routine genetic screening and prenatal diagnoses for diseases such as Duchenne muscular dystrophy and cystic fibrosis.

The first government - funded human genomics research study performed on African soil — aimed at unlocking the unique genetic character of southern African populations — has revealed a high level of genetic diversity.

To do that, his lab performs comparative studies on the genetic characteristics of both the mutualistic symbiont and its «wild» progenitor.

So I clicked on it: «Because genetic association studies are generally performed in populations of a particular ethnic background [European, Asian, African], we can not know whether the associations will also apply to those of a mixed background.

Hawass, Pusch and 15 other scientists continue to perform detailed anthropological, radiological and genetic studies on the precious mummies in a lab built into the basement of the Museum of Egyptian Antiquities in Cairo — two floors below the famous golden mask.

A University of Colorado Cancer Center study published in the journal Oncogene used next - generation sequencing technologies to perform the most detailed DNA - based analysis to date of 25 commonly used bladder cancer cell lines, allowing researchers to match patient tumors with their closest genetic cell line match, and demonstrated genetic alterations that may make cells more or less sensitive to common therapies.

Extensive genetic studies of this plant have already been performed, its genome sequenced and DNA transfer methods established.

Preliminary genetic evidence included in the study suggests that the enzyme, called SNRK, performs similar functions in humans, making it an intriguing new drug target in the battle against obesity and its complications.

Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations.3

A new study sheds light on the genetic balancing act these lady salamanders perform to survive and thrive.

In 2013, an expert panel made up of members of the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology published guidelines describing the genetic tests that should be performed to evaluate a patient's lung cancer.

The ICS is a large - scale facility open to the community that ensures the generation of mouse models à la carte, the validation of genetic models, the expansion and preservation and distribution of models with the housing department, and offers in its phenotyping department a series of standardized functional analysis of mouse models that can be performed in a comprehensive pipeline or on demand, as well as for more specialized studies, that cover the major functions and key physiological systems.

These data will be used to perform genetic and evolutionary studies to learn where parasites originate, how they spread and how different strains are distributed geographically.

In this way, in - depth immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic studies can be designed and animal modeling performed.

Methods: We performed a retrospective study in two French genetics laboratories by gathering all clinical and neuroimaging data from patients referred for a genetic diagnosis of CAA with an age of onset before 66 years and fulfilling the other Boston revised criteria.

Dr. Talkowski has performed seminal studies to introduce high - resolution genomics techniques to delineate the types of genetic variation that were classically defined using cytogenetic methods, which has discovered new classes of complex genomic variation in the human genome that are remarkably common yet otherwise cryptic to conventional technologies.

Here, Kiel and colleagues perform a meta - analysis of genome - wide association studies for whole body lean body mass and find five novel genetic loci to be significantly associated.

For the study, Levine and his colleagues performed genetic analyses of ovarian cancer cells from 96 patients.

Here are the facts compiled from genetic DNA studies performed at Louisiana State University, Texas A&M University, Cornell University, Auburn University, Clemson University, and the University of Virginia.

It is, therefore, no surprise that a number of genetic studies have been performed in this breed, with results proposing a single major gene with a large effect on seizures 8, 24 - 26.

Evidence has emerged of a possible genetic correlation in dogs because of the higher prevaience of lymphoma in certain breeds, but further studies need to be performed to determine the exact risk factors involved in canine lymphoma.

Recently, a research team from Denmark performed a large population - based and register - based prospective cohort study to shed further light on this compelling issue.13 Researchers included only singleton births in a 10 - year period, and excluded conditions associated with an increased risk of ASDs (eg, congenital rubella syndrome or some genetic disorders in parents).

These studies are performed using molecular genetic studies, where DNA is extracted from participants» blood samples and the correlation between the DNA and the observed behavior is projected.