Sentences with phrase «performing preclinical»

The George lab is currently performing preclinical studies for the future development of novel therapeutic approaches including Deep Brain Stimulation, Optogenetics, Chemogenetics and Precision medicine.

The researchers are currently putting together an international, strong medical team to start performing preclinical studies.

«The next step is to perform preclinical studies with specific inhibitors of HDAC11 alone and in tandem with other existing immunotherapies, such as anti-PD1 / anti-PDL1 antibodies, in order to find the most potent combination.

Bryan's group has designed a BiTE against the EGFRvIII tumor - specific antigen, which is expressed in a majority of glioblastoma cases, and has performed preclinical tests to determine its efficacy against EGFRvIII - expressing glioblastoma.

Not exact matches

«It performed so well in the preclinical model, we determined that to boost its effects further was essentially impossible,» said Orme, also a co-founder of CSU's Mycobacteria Research Laboratories.

Presently there is no reliable biomarker for Parkinson's disease, either at the diseased or preclinical state, except for dopamine - based PET imaging, which is costly and requires highly specialised skills to perform.

Moreover, these preclinical imaging approaches provide the unique opportunity to perform longitudinal studies of the same animal, minimizing experimental variability and number of animals per study.

M1: Passive transfer studies in preclinical model performed; Report on protection by passive therapy with human immune IgG

and affinity of antibody ACI - 5400 were characterized by a panel of methods: (i) measuring the selectivity for a specific phospho - Tau epitope known to be associated with tauopathy, (ii) performing a combination of peptide and protein binding assays, (iii) staining of brain sections from mouse preclinical tauopathy models and from human subjects representing six different tauopathies, and (iv) evaluating the selective binding to pathological epitopes on extracts from tauopathy brains in non-denaturing sandwich assays.

BIRMINGHAM, Ala. — April 7, 2016 — Paul Bushdid, Ph.D., has joined Southern Research to lead its Developmental & Reproductive Toxicology (DART) program, which performs complex preclinical studies to ensure -LSB-...]

Performs genome - wide profiling of vector integration sites as readout of cell growth at clonal level, in basic research studies and technology development, in preclinical safety studies and in gene therapy treated patients.

In fact, preclinical studies have been performed to investigate each of these modalities [73 — 76], and human clinical trials are in progress (European Union Clinical Trials Register # 2014 -000350-11).

The authors thank Shengbin Yang from the Johns Hopkins Lung Disease Preclinical Model Core for performing the animal exposures.

To assess whether a dog has preclinical MMVD, a thorough history and physical examination should be performed at every visit.