We have identified another family required for RNA editing by immunoprecipitating ORRM1 and
performing proteomic analysis in collaboration with the Van Wijk lab.
Not exact matches
For gene expression
analysis, microarrays were
performed by the DKFZ Genomics and
Proteomics core facility (Heidelberg, Germany).
A
proteomic analysis by mass spectrometry will be
performed in serum.
In this way, in - depth immunological monitoring, genetic and
proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic studies can be designed and animal modeling
performed.
We then
performed neuroanatomical
analyses to validate
proteomic findings and analyzed additional proteins that were suggested by
proteomic findings.