«In order to completely relieve jet lag, it is necessary to adjust both the central and
peripheral circadian clocks.
Not exact matches
But
circadian rhythms are also present in
peripheral «
clocks» in many cell types.
Results suggest a revised model of
circadian entrainment, with the adaptation of the internal
clock by external time cue, resulting in a mode of photic entrainment in which light can in parallel reset central and
peripheral clocks.
This challenges and disproves the commonly held notion that
circadian rhythms were strictly organized in a hierarchical manner, and that light resets the master
clock in the SCN, which then coordinates the other, subordinate
clocks in
peripheral tissues.
«This suggests that resetting specific
peripheral tissue
clocks may be an underestimated target for restoring
circadian alignment, and possibly to counteract disorders associated with
circadian rhythm disruption.»
This research is important, however, because it not only shows us what might be going wrong in folks with
circadian - related disorders, but also helps us to understand how we can manipulate
peripheral clocks to help these people.»
The
clock genes that govern the 24 - hour
circadian rhythms of the body also function in similar cycles in
peripheral cells outside the brain, researchers have found.
According to Dr. Lori Rose, who is my co-author for this post, that's because our digestive tract contains a «
peripheral body
clock» that syncs up with our 24 - hour
circadian rhythm, and periods of daily feasting / fasting help «set» the
clock in the same way that light and dark does.
These findings demonstrate that the adipocyte
circadian clock acts at the interface between the central nervous system and the predominant
peripheral energy storage tissue to coordinate the temporal organization of feeding behavior and maintain energy balance.