Sentences with phrase «personalized cancer therapy»
«Next generation sequencing tools were used to profile patients» tumors,» said Razelle Kurzrock, MD, director of the Center for Personalized Cancer Therapy at UC San Diego Moores Cancer Center.
sciencedaily.com
«These studies form a proof - of - principle demonstration of the ability of computer modeling to be used to choose therapy for individuals,» said Razelle Kurzrock, senior deputy director (clinical science) and director of the Center for Personalized Cancer Therapy at UCSD Moores Cancer Center, and senior author of this paper.
Hoping to cash in on personalized cancer therapy, a new company called Foundation Medicine — founded in part by genome guru Eric Lander of the Broad Institute — plans to develop tests for genetic glitches in tumors that make them vulnerable to specific drugs, reports the United Kingdom's Times Online.
In the era of personalized cancer therapy, patients with TNBC remain at considerably higher risk of relapse and death than patients with other breast cancer subtypes, due to the aggressive nature of TNBC and the lack of newer targeted therapies for the disease.
This has always been at the core of IBM's approach to using big data analytics to boost personalized cancer therapy.
«Oncologists here at Moores Cancer Center at UC San Diego Health and elsewhere can often personalize cancer therapy based on an individual patient's unique cancer mutations,» said senior author Trey Ideker, PhD, professor of genetics at UC San Diego School of Medicine.
The findings support investigation of FL118 as an MdmX - depleting agent in MdmX - targeting personalized cancer therapies.
While there is still work to do before a treatment is available, the hope is that these findings will help to target other cancers with similar weak points and provide a step towards personalized cancer therapy.
«Nanodiscs deliver personalized cancer therapy to immune system.»
«We have found that molecular diagnostics play an important role in patient care when paired with the expertise of a molecular tumor board,» said Maria Schwaederle, PharmD, lead author and a researcher in the Center for Personalized Cancer Therapy.
«We hope that iCAGES can help clinicians take full advantage of the massive amounts of data on genomic sequencing and cancer variants, and shed light on personalized cancer therapy,» said Dr. Wang.
«Our analysis shows that in the era of precision medicine, phase I clinical trials using personalized therapy with a biomarker - based approach can do more than assessing the toxicity and side effects,» said Maria Schwaederlé, PharmD, lead author and UC San Diego Moores Cancer Center researcher at the Center for Personalized Cancer Therapy.
«Researchers ID cancer gene - drug combinations ripe for precision medicine: Yeast, human cells and bioinformatics help develop one - two punch approach to personalized cancer therapy.»
Personalized cancer therapies could be developed by targeting breast cancer cells that express copious levels of IL13RA2,» explained corresponding author Sam Thiagalingam, PhD, associate professor of genetics & genomics, medicine and pathology & laboratory medicine at BUSM.
This is our dream for personalized cancer therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem cell genomics at the UCSC Genomics Institute, and a senior corresponding author of the paper.
The MD Anderson Cancer Center Sheikh Khalifa Bin Zayed Al Nahyan Institute for Personalized Cancer Therapy is home to an integrated clinical cancer research and clinical trials program that is aimed at implementing personalized cancer therapy and improving patient outcomes.
Similarities between genetic signatures in developing organs and breast cancer could predict and personalize cancer therapies.