We made history in August 2017 when the FDA approved
a personalized cell therapy for advanced leukemia, the first - ever for cancer cell and gene therapy.
Dr. Kim's lab also investigates translational stem cell research and
personalized cell therapy of PD and is optimizing reprogramming and differentiation methods.
«
Personalized cell therapy combination achieves complete remission in CLL patients: Latest results from trial investigating CAR therapy to treat CLL.»
This accomplishment opens the door for disease modeling and drug screening and brings
personalized cell therapy a step closer for patients with diabetes.
«This newer, coupled approach gives us hope that
personalized cell therapies could be an important option for high - risk CLL patients on these types of drugs.»
Not exact matches
He's now the executive chairman of Rubius Therapeutics, a biotech firm that's also working with
cell therapy to develop treatments like Kymriah that don't have to be as
personalized.
Enabling scientists to grow the stem
cells artificially from pluripotent stem
cells could also lead to the development of
personalized blood
therapies, researchers say.
Another strategy, which Steinman and others were studying, involves a
therapy to target dendritic
cells inside the body rather than taking them out and
personalizing therapy for each patient.
We hope this leads to the ability to design, study and test new
therapies for every patient on their own
cells in the lab, leading to new treatments and breakthroughs in
personalized medicine for individuals with a variety of lung diseases, including cystic fibrosis,» explained lead author Katherine McCauley, a PhD student at BUSM.
In an effort to expand the number of cancer gene mutations that can be specifically targeted with
personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer
cells.
«Researchers ID cancer gene - drug combinations ripe for precision medicine: Yeast, human
cells and bioinformatics help develop one - two punch approach to
personalized cancer
therapy.»
«This could lead to
personalized therapy where we can look at how an individual's
cells respond to different therapeutic cocktails,» said Mirkin, whose lab developed NanoFlares in 2007.
Ploegh envisions the technique being used to create a new type of
personalized therapy in the future — your own
cells could be isolated, used to create stem
cells that differentiate into erythroblasts, genetically modified to carry a molecule, and reinjected into your body.
«Our long term goal is to develop a
personalized cell replacement
therapy using a patient's own
cells to treat boys with Duchenne,» said Hicks.
This is our dream for
personalized cancer
therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem
cell genomics at the UCSC Genomics Institute, and a senior corresponding author of the paper.
A new model for post-integration latency in macroglial
cells to study HIV - 1 reservoirs of the brain, AIDS, DOI: 10.1097 / QAD.0000000000000691 Link to the original publication As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing
personalized medical approaches for the prevention and
therapy of major common diseases such as diabetes mellitus and lung diseases.
And because a patient's
cells are harvested and returned to her, it is
personalized therapy.
Due to the high efficiency of establishing organoid models from different tissues and diseases, such as cancer, organoid technology allows the generation of large living biobanks of tumor organoids that are amenable for middle - throughput drug screens and may allow
personalized therapy design, as a complement to
cell line and xenograft - based drug studies (7,19).
The new iPS
cells generated using novel methods may represent biomedically - and clinically - ideal
cells, providing potential platforms for studying human disease mechanisms and achieving the long - term goal of
personalized cell - replacement
therapy.
While such a cluster of
personalized cells is not a perfect replica of the organ that exists in that person's body, it can be experimented on and used to gauge the effectiveness of potential
therapies, providing a powerful new tool to help researchers understand how diseases develop and how to treat them.
These rECs could be valuable for
cell therapy,
personalized disease investigation, and exploration of the reprogramming process.
«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly
personalized modeling of kidney diseases and drug toxicities, and the stem
cell - derived kidney podocytes we developed could even offer a new injectable
cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.
And the ability to efficiently and precisely modify the DNA in these
cells offers enormous potential for the development of
personalized stem
cell therapies that benefit people with many different types of genetic disorders.
About Blog Assisting individuals with Personal Cellular Storage for Regenerative Medicine and
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