Widespread
pertussis vaccine use at a Florida preschool failed to keep the disease away from about three dozen students, staff and family members
Not exact matches
The older
vaccine, DTP,
used whole cells of the
pertussis bacterium but had more dramatic side effects, often causing high fevers and sometimes fever - induced seizures.
A combination
vaccine called the DTaP (for diphtheria, tetanus, and acellular
pertussis) protects children up to six years old from
pertussis, and a similar formulation called Tdap is
used to protect older children and adults.
Before the
pertussis vaccine entered routine
use in the 1940s, the bacterial infection killed about 4,000 people a year in the United States.
Before
pertussis vaccines came into
use in the 1930s, the infection killed about 4,000 Americans (mostly infants) a year — 10 times as many as the number of people who died annually from measles and 12 times more than died from smallpox.
The bacterium that causes whooping cough, Bordetella
pertussis, has changed in Australia — most likely in response to the
vaccine used to prevent the disease — with a possible reduced effectiveness of the
vaccine as a result, a new study shows.
Pertactin is one of the three proteins, made from purified extracts of Bordetella
pertussis bacteria, which are present in the
vaccine currently
used in Australia.
The recent increase in cases of whooping cough among teenagers in the US suggests that the protection conferred by the acellular Bordetella
pertussis vaccine (aP) that became standard in the mid 1990s is of shorter duration than that conferred by the whole - bacteria formulation (wP)
used since the 1950s.