Sentences with phrase «phage library»

With no candidate targets, the team took an objective approach by applying a peptide phage library to MDSCs, which permitted mass screening for candidate peptides — short sequences of amino acids — that bind to the surface of the MDSCs.

Deep sequencing of the VHH phage libraries generated from a set of llamas, which received two different immunization protocols, showed that the new VHH and the previously described anti-HIV VHH J3 [26] were induced by immunization (Table 1).

These phage libraries have tremendous diversity, so you can use them to find very unique antibody protein sequences that target specific molecules within disease pathways,» says Coyle.

Not exact matches

A new technique of direct binding of radioactive DNA was used to screen a complementary DNA expression library from the BJAB cell line in lambda gt11 phage to derive molecular cDNA clones representing a putative B lymphocyte - specific octamer binding protein.

4.4 Technologies for Generation of TCRL Antibodies 4.4.1 TandAb 4.4.2 BiTE 4.4.3 E-Alpha Phage Display 4.4.4 HuTARG Protein Engineering 4.4.5 MAR & TriTE 4.4.6 TCRL Antibodies 4.4.7 TCRm Antibodies 4.4.8 Ylanthia Fab library 4.4.9 TCRL ADCs

Obtained as a Fab by selection against gp120 IIIB of an antibody phage display library prepared from bone marrow of a asymptomatic HIV - 1 seropositive donor.

Around the same time that transgenic mice began to be used to produce human antibodies, scientists also started employing a genomic technology called phage display to build massive libraries of human antibody genes that could be screened quickly.»

Human Antibodies From V - Gene Libraries Displayed on Phage», Journal of Molecular Biology, 222: 581 - 597, 1991.

He was a postdoctoral scientist at Applied Molecular Evolution, where he produced and screened random peptide phage display libraries with soluble empty mouse CD1 (mCD1) to identify a peptide - binding motif for MHC Class I like receptors.