Engineered
phage viruses show promise as targeted assassins - genetic manipulation might make it easier for them to gain regulatory approval
Not exact matches
Patients in danger of dying from uncontrollable bacterial infections could find new allies: killer
viruses known as
phages.
These
viruses, called bacteriophages or just
phages, naturally latch onto bacteria to infect them (SN: 7/12/03, p. 26).
Phages are
viruses that infect only bacteria.
The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by
viruses that attack them, known as
phage, and has even been shown to protect animals from fatal infection by Bacillus anthracis, the bacteria that causes anthrax.
Bacteriophages, also known as «
phages,» are
viruses that infect and kill bacteria.
We use
viruses called
phages that infect bacteria but not human cells.
«This is going to be one of those transformative papers,» says microbiologist Martha Clokie, who studies
viruses that infect bacteria (known as bacteriophages, or
phages) at the University of Leicester, UK.
Here, hordes of
viruses known as
phages assault a bacterium to turn it into a
virus - making factory.
Phage therapy, which exploits the ability of certain
viruses to infect and replicate within bacteria, shows promise for treating antibiotic - resistant bacterial infections.
A
phage means bacteria eater and so they were very specific hosts, which is a very specific bacteria, and we like these
viruses a lot because they only have a couple different genes and those genes code for a couple different proteins and so they are easy for us to manipulate in the lab.
«A
phage is a
virus that specifically infects a bacterium so it can't infect people and it can't infect animals and it can't infect plants.
Research focused on the utilisation of
viruses that infect and kill bacteria, known as bacteriophages or
phages, in preventing infectious diseases has gained new traction after bacterial resistance to antibiotics has become a global problem.
Transferring just the bacteriophage (
phage)--
viruses that infect the microbiome bacteria — was sufficient to reduce resting metabolic rate and cause weight gain in control mice.
As other
viruses do,
phages enter susceptible cells and insert their own genes.
A
phage is a type of
virus that attacks and infiltrates bacteria.
Bacteria are vulnerable to deadly
viruses called
phages, which can hijack bacteria's genetic machinery and force them to produce viral DNA instead.
Gut
viruses called bacteriophage, or
phage (red), harbor resistance genes that shield bacteria from antibiotics.
Bellen and Venken attached artificial docking sites to
phages — a
virus that targets bacteria — which they introduced in both the bacteria and in the fruit fly genomes to act as sticky points for the DNA segment being implanted in the latter's genome.
Bacteriophages, or simply
phages, are
viruses that infect and replicate within bacteria, and they hold considerable potential for combatting antibiotic - resistance and other threats to human health.
It attacked Pseudomonas through its pump, a molecule called outer - membrane - porin M. Chan dubbed the
virus of his dreams OMKO1 (short for outer - membrane - porin M knockout dependent
phage # 1).
Thomas G. Bernhardt of Texas A&M University and his colleagues found the protein in a tiny
virus, or
phage, known as Q Beta.
For eons, bacteria have battled particularly tiny
viruses called bacteriophages, or
phages for short, which infect and kill bacteria but leave humans and other animals alone.
They also noticed that the new
virus, named Bacillus
phage Tsamsa, is unusually large, with a giant head, a long tail and a large genome, placing it among the largest known bacteriophages.
Mucus is also home to
phages,
viruses that infect and kill bacteria.
Based on the genetic blueprint, these bacterial cells then produce all the components of the desired
phage and ensure that the
virus particles are assembled correctly.
But scientists hadn't yet explored whether
phages —
viruses that infect bacteria — were part of this shared community.
And even if there were any, for example due to a bacterium changing its surface structures to prevent the
virus from attaching, the new technology makes it possible to develop a suitable
phage against which a bacterium has not yet developed resistance.
This keeps the
phages in the mucus, where they have access to bacteria, and suggests that the
viruses and the mucus - producing tissue have adapted to be compatible with each other, the team reports online today in the Proceedings of the National Academy of Sciences.
«To solve this problem, we borrowed a tool from
phages themselves: the enzymes these
viruses use to break apart a
phage - infected cell to release their progeny,» says Douglas Deutsch, a graduate student in the lab.
A new technique allows researchers to examine pieces of often - overlooked DNA outside bacterial chromosomes, including
viruses known as
phages (as shown above), which may play a role in disease.
Extrachromosomal DNA can include bacteria - infecting
viruses, known as
phages, and strands of self - replicating DNA, known as plasmids, often picked up from other bacteria.
The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system was originally discovered by dairy industry researchers seeking to prevent
phages, the
viruses that infect bacteria, from ruining the cultures used to make cheese and yogurt.
Phages and
viruses ** Viral insulin - like peptides activate human insulin and IGF - 1 receptor signaling: A paradigm shift for host - microbe interactions.
After the last coffee break Emmanuelle Charpentier (Umeå University, Sweden) entered the scene and shared her knowledge about how to use
phages (
viruses that target bacteria) for genome engineering via CRISPRs.
Young's research focuses on bacterial
viruses, also known as bacteriophage or
phage.
Also presented are possible alternative approaches to tackling infections, such as
phages (
viruses that kill bacteria) sourcing new antibiotic leads from oceans, soils and host - associated microbiomes in humans, komodo dragons and leafcutter ants.
Some of the them are
phages and infect my bacteria, and others are plant
viruses.