Sentences with phrase «phages in»

This keeps the phages in the mucus, where they have access to bacteria, and suggests that the viruses and the mucus - producing tissue have adapted to be compatible with each other, the team reports online today in the Proceedings of the National Academy of Sciences.

Nevertheless, in this research two limitations were observed in the use of orally administered bacteriophages: the reduced stability of the phages in extremely acid environments, such as the stomach, and short residence time in the intestinal tract.

Protective phages seem to be equally widespread: Barr and his colleagues found dense populations of phages in every species they sampled.

Some bacteria protect themselves against phage attacks with a system called CRISPR, which stores pieces of past invaders» DNA so bacteria can recognize and fend off those phages in the future (SN: 4/15/17, p. 22).

«Phage treatment was effective in inhibiting bacterial growth in food, while the number of phages in the food grew, indicating that phages infect bacteria and grow in them also when refrigerated,» says Skurnik.

Next, the researchers inoculated kitchen utensils, such as wooden and plastic cutting boards, knives and surgical gloves, with the bacteria and phages, after which the number of bacteria and phages in the utensils was monitored for two hours.

To the best of Skurnik's knowledge, corresponding studies on the application of phages in food treatment have not been conducted anywhere prior to this.

«We can sequence a phage quickly and say, this is the exact DNA sequence we want,» says Paul Grint, CEO of AmpliPhi Biosciences, a startup that is concocting combinations of phages in advance to treat bacterial infections like Staphylococcus aureus.

Probio Flora too is uhm — the Phage in there really helps kill uh — E.coli too.

Dr. Justin Marchegiani: Probio Flora too is uhm — the Phage in there really helps kill uh — E.coli too.

Not exact matches

Patients in danger of dying from uncontrollable bacterial infections could find new allies: killer viruses known as phages.

Eventually, Merril sees an AI app being used in hospitals in combination with a dispensing system that could identify the most effective phage or combination of phages and distribute a vial to treat a patient within minutes.

Phages often live in dirty places, including sewage, so scientists must first isolate and purify them.

In addition to bakery and dairy processing equipment, the facility also features analytical, phage test and sensory equipment, which includes a texture analyser, rapid visco analyser, viscometer, water activity and colour meter, meltdown analyser, high - resolution microscope, auto titrator, humidity chambers and ambient shelf storage.

For example, the phages exposed E. coli in milk and orange juice by turning the liquids red or pink.

In contrast, phages «exist everywhere,» making them potentially more broadly useful as bacteria hunters, Nugen said.

The researchers embedded phages into soluble «sugar glasses» or films made with pullulan, a polysaccharide used to prolong the shelf life of fruits and eggs; trehalose, a sugar used as stabilizing agent in freeze drying; or a combination of two substances.

«This is just the first in what will likely be numerous studies into the phage diversity of the urinary microbiome,» said Dr. Putonti.

The investigators found a total of 457 mostly novel phage sequences in the urinary microbiome.

Because phages are naturally found on fruits and vegetables and do not affect the odor, taste, safety or appearance of foods, scientists are investigating whether these «bacteria - eaters» could have an expanded role in promoting food safety.

«This first step in the characterization of the phages already present within the bladder has the potential to identify candidates for subsequent phage therapy clinical studies for urinary symptom treatment.»

«Phage have been used as an alternative to antibiotics for decades in eastern European countries, particularly for treatment of urinary tract infections,» said corresponding author Catherine Putonti, PhD, Associate Professor of Bioinformatics, Loyola University, Chicago.

Phages embedded in pullulan or trehalose alone lost their antibacterial effects within one or two weeks.

The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage, and has even been shown to protect animals from fatal infection by Bacillus anthracis, the bacteria that causes anthrax.

«In this study, we proved that C. sakazakii - phage CR5 is an efficient biocontrol agent in infant formulIn this study, we proved that C. sakazakii - phage CR5 is an efficient biocontrol agent in infant formulin infant formula.

There was some variation in the abundance of phages from healthy bladders vs. those isolated from women with symptoms of urinary tract infections.

In the study, the phage, called «CR5,» showed high antimicrobial activity against the bacterium, Cronobacter sakazakii, as well as against several other species of Cronobacter, which can also cause dangerous illness, said coauthor Sangryeol Ryu, professor in the Department of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, KoreIn the study, the phage, called «CR5,» showed high antimicrobial activity against the bacterium, Cronobacter sakazakii, as well as against several other species of Cronobacter, which can also cause dangerous illness, said coauthor Sangryeol Ryu, professor in the Department of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Korein the Department of Agricultural Biotechnology, Research Institute of Agriculture and Life Sciences, Seoul National University, Korea.

About this Book: Life in Our Phage World: A Centennial Field Guide to the Earth's Most Diverse Inhabitants Forest Rohwer, Merry Youle, Heather Maughan, and Nao Hisakawa Wholon, 2014

When levels of arbitrium build up — after a large number of cells have died — phages stop killing off the remaining bacteria and retreat to lie dormant in bacterial genomes instead.

A phage means bacteria eater and so they were very specific hosts, which is a very specific bacteria, and we like these viruses a lot because they only have a couple different genes and those genes code for a couple different proteins and so they are easy for us to manipulate in the lab.

Treating food with phages is not, however, an entirely novel idea: in the United States, a phage product already on the market is sprayed on raw food products to prevent Listeria bacteria growth.

Now, in cooperation with researchers at the Seoul National University in South Korea, he has been investigating the possibility of utilising phages also in eradicating foodborne pathogens and preventing food poisoning.

In this case as well, the phages effectively inhibited bacterial growth.

Begun in 2007, SEA - PHAGES now supports students at 110 institutions in 39 states.

So - called phage therapy is widely used in Eastern Europe and is currently undergoing one U.S. clinical trial.

Students in the program learn to isolate and characterize bacteriophages, annotate the phage genomes, and then submit the sequences to a national database.

Research focused on the utilisation of viruses that infect and kill bacteria, known as bacteriophages or phages, in preventing infectious diseases has gained new traction after bacterial resistance to antibiotics has become a global problem.

Transferring just the bacteriophage (phage)-- viruses that infect the microbiome bacteria — was sufficient to reduce resting metabolic rate and cause weight gain in control mice.

In 1998, Sulakvelidze helped found the biotech company Intralytix, which has successfully devised a number of food safety products, including a spray that uses phages to eradicate Listeria, Salmonella and E. coli in foods before they reach storeIn 1998, Sulakvelidze helped found the biotech company Intralytix, which has successfully devised a number of food safety products, including a spray that uses phages to eradicate Listeria, Salmonella and E. coli in foods before they reach storein foods before they reach stores.

Each strain of phage is highly targeted and has evolved to home in on specific bacteria, which means a precise match between prey and predator is necessary for any phage - based treatment to be effective.

Phages would require a less traditional approach to get official approval, such as the annual process for influenza vaccines in which manufacturers secure approval of new formulas based on the flu bug that is going around that year, instead of conducting big clinical trials every time.

We haven't quite gotten there yet — but when we do, phages will be waiting in the wings.»

The comeback of antibiotic - resistant infections «would dramatically alter the practice of medicine,» says microbiologist Alexander Sulakvelidze, a phage expert at the Emerging Pathogens Institute at the University of Florida in Gainesville.

Somehow, the tiny phages sneaked in and overpowered the much larger cholera cells, using a big chunk of this stolen immune system.

Indeed, the lack of any flavor in phage mists might even give them an advantage over alternatives — such as vinegar mists or chlorine baths — for sanitizing salad greens.

That company has been gaining renown for pioneering exploitation of phages to quash a host of food poisoning agents in other venues, such as meats (SN: 6/3/00, p. 358).

Thats good, Leverentz adds, since you wouldnt want any of the phages delivered in the kitchen to also wipe out beneficial microbes, such as some lactobacilli.

Phages are still routinely used in Eastern Europe and, more recently, in Asia.

Leverentz says that her preliminary tests indicate phages may even find use one day in sanitizing counters, cutting boards, and kitchen utensils.

A tiny phage attacks an E. coli cell in this false - color image from a transmission electron microscope.