Sentences with word «phagocyte»

In response to fatty deposits on the walls of the arteries, a type of phagocyte called a macrophage identifies the growing lesions as trouble spots and infiltrates them, swelling and destabilizing the deposits.

Some evidence suggests that neutrophils continue to act as phagocytes in the infant's gut.

People born with CGD lack an enzyme called phagocyte NADPH oxidase, which white blood cells use to make the hydrogen peroxide needed to kill microbial invaders.

CX3CR1 + phagocytes dwell in the gut lining and were already known to defend the gut by engulfing bacterial cells and even food - derived plant and animal cells.

Her major scientific contributions have centered on defining the importance of mononuclear phagocyte function in resistance to infection and inflammation, defining the interaction of pathogens and commensal bacteria with epithelial cells in homeostasis and inflammation, and experimental reproducibility.

Vomocytosis is a process adopted by phagocytes to eject the pathogens they can no longer destroy.

While the complement system slimes the area, an assemblage known in immunology textbooks as professional phagocytes — literally «expert eating cells» — goes to work.

, a product of activated phagocytes, can be oxidized to electronically excited singlet oxygen (O1 (2) delta g), an agent that is capable of peroxidation of unsaturated fatty acid derivatives.

We are therefore unable to visualise the outcome of the first interactions between insect phagocytes and invading microbes, interactions that will determine the future success of the infection itself.

From this, PNH erythrocytes become increasingly coated with C3 fragments, turning them into tasty meals for cell - engulfing phagocytes, a specialized cell in the body's recycling system.

The Society for Leukocyte Biology (SLB) Symposium Early Career Investigators: Tissue Phagocyte Heterogeneity in Health and Disease Monday, May 7, 10:15 AM — 12:15 PM, Room 18CD Chairs: Robert A. Clark, Univ. of Texas Hlth.

influenza B Haemophilus influenza Type B (THE FLU), polyribosylribitol phosphate (A FLU COMPLEX CONJUGATE - DISABLES THE FLU PHAGOCYTE), ammonium sulfate (A PURIFICATION AGENT), formalin (A FORM OF FORMALDEHYDE, USED TO DISABLE THE FLU VIRII), and sucrose (SUGAR).

In Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure: Critical Importance of the Cardiosplenic Axis, Prabhu and colleagues showed that immune cells that are stored in the spleen were intricately involved in the heart failure that follows a heart attack, or infarction, in a mouse - model system.

In order to investigate the migratory mechanisms of various phagocytes, researchers usually study genetically modified mice which display inflammatory diseases.

«In the initial phase, epithelial cells act as non-professional phagocytes to clear up milk protein and milk fat globules.

«It keeps the inflammatory phagocytes at bay, by getting the epithelial cells to do the job of clearing themselves up,» Streuli adds.

Mice lacking gut CX3CR1 + phagocytes turned out to be far more susceptible to intestinal disease than mice that still had the antifungal cells.

Retinal cell death can be induced by phagocytic immune cells that infiltrate the tissue in response to injury or infection, but the molecular signals that trigger phagocyte invasion are largely unknown.

The cytokine then binds to its receptor on the surface of the Müller cells and induces the release of additional inflammatory proteins that attract phagocytes to the damaged retina.

A team of researchers led by Hongkang Xi and Menno van Lookeren Campagne, of the Department of Immunology at Genentech, Inc., in South San Francisco, Calif., discovered that a pro-inflammatory signaling protein, or cytokine, called IL - 33, plays a key role in recruiting phagocytes to damaged retina and inducing retinal degeneration.

«This is a protein complex that integrates multiple pieces of signaling information in macrophages, special phagocytes that reside in tissues.

The ISS experiment focuses on the long - term impact of zero gravity on human phagocytes — especially their cytoskeleton and molecules, which are important for cell communication.

In people with CGD, phagocytes lack the hydrogen peroxide they need to kill microbial invaders and instead form areas of swollen tissue known as granulomas.

Richard Karp, an immunologist at the University of Cincinnati in Ohio, agrees that this is «an intriguing piece of work,» but cautions that there are «lots of loose ends to pull together,» such as how phagocytes can develop specificity against particular microbes.

In zero gravity, for instance, various immune system functions are impaired: Phagocytes known as macrophages, which kill and destroy invading bacteria, are no longer capable of protecting the person optimally from infections, which is why astronauts often suffer them.

In contrast, we show that the cells of the insect pathogen Photorhabdus instantly freeze the highly mobile phagocytes.

This centenary coincides with a surge of new molecular and cellular information about phagocytes that crosses traditional disciplinary boundaries.

2016 marks the centenary of the death of Elie Metchnikoff, the Russian scientist who first discovered phagocytes.

The newly described mechanism involving gastric immunoregulatory mononuclear phagocytes brings an improved understanding of the complex and dynamic interactions between H. pylori and its human host.

Infection of cells by dengue or West Nile viruses is markedly enhanced when phagocytes express receptors that recognize and bind PS.

Mutations typically affect the ability of certain phagocytes to eat and destroy pathogens effectively.

Several cells of the immune system can store vitamin C and require it to perform their task, especially phagocytes and t - cells.

In several preliminary studies — including one study of older individuals (with an average age of 86 years) consuming one half ounce of probiotic cheese every day for 4 weeks — researchers were able to detect immune system benefits, including increased activity of immune cells and increased numbers of some immune cell types (particularly phagocytes).

She refocused her work on how those dying cells are recognized and engulfed by clean - up cells called phagocytes.

However, after about three days in the mouse, macrophages (and other professional phagocytes) enter the gland and clear away the remaining cells and debris.»

Antifungal drug treatment significantly reversed signs of the disease in the mice lacking CX3CR1 + phagocytes, indicating that fungal overgrowth had been the cause.

One possible mechanism of the action of Au (I) compounds is that they protect unsaturated membrane lipids and proteins against oxidative degradation caused by activated phagocytes that are not properly regulated.

Access to both purified Mcf1 toxin and recombinant E. coli expressing the mcf1 gene makes this an ideal virulence factor in which to study early interactions between an insect pathogen and insect phagocytes.

In the new study, Dr. Iliev and his colleagues largely answered that question by identifying a type of white blood cell, the CX3CR1 + mononuclear phagocyte, as the immune system's major gut fungal regulator.

It mediates the immune response, enhances the production of virus - fighting interferon, and boosts the function of phagocytes — immune system cells that engulf and destroy pathogens.

It is possible, for example, to examine the effects of a recombinant bacterial toxin on infection, but it is more difficult to examine the role of specific virulence factors in neutralizing specific elements of the immune system, such as phagocytes.