Sentences with phrase «phagocytized by macrophages»

«Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages»

Analysis of the tumour showed that it also been infiltrated by macrophages.

They first showed that mice with severed sensory nerves produce excessive BH4, churned out both by the injured nerve cells themselves and by macrophages — immune cells that infiltrate damaged nerves and inflamed tissue.

Biologic therapy removes the protein molecules being secreted by the macrophages.

m), where we can see the seminiferous tubules (red) surrounded by macrophages (green).

«How tattoos are maintained by macrophages could be key to improving their removal.»

These proteins most closely resembled those made by endothelial cells in the lymphatic system, not the proteins made by macrophages or other immune cells.

They can be phagocytized by macrophages and cleared out of the body.»

Most dangerous bacteria are attacked by macrophages.

«The current model of disease is that when Mtb bacteria are inhaled, they reach the end of the lung — the alveolus — and then are ingested by a macrophage, a type of white blood cell that swallows and kills invading bacteria,» Dr. Shiloh said.

«First, the effect of cortisone is mediated by macrophages which usually serve as scavenger cells in an immune response.

Thirty percent of the 100 most significantly correlated transcripts encoded proteins characteristically expressed by macrophages, such as the CSF - 1 receptor (τ statistic = 0.60, P = 4.5 × 10 — 5) and the CD68 antigen (τ statistic = 0.75, P = 2.9 × 10 — 7).

Amyloid beta plaques (in green) surrounded by macrophages carrying a receptor for antibodies (in red).

Nos2 was expressed by both macrophages and F4 / 80 — SVCs, and Il6 was detectably expressed by all three populations in adipose tissue.

A paper from cardiologist Aloke Finn and colleagues (published Wednesday, Aug. 5 in Nature Communications) describes how the protein CD163, produced by macrophages, puts the brakes on muscle repair after ischemic injury in mice.

Evidence suggests that the resolution of infection and thus inflammation is prolonged due to reduced clearance of apoptotic cells and debris by macrophages.11 These age - associated alterations in innate immunity may contribute to increased systemic inflammation termed «inflamm - ageing» observed in aged tissues.10

Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN - γ in a nitric oxide - dependent manner.

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage - mediated inflammation in muscle.

Is this the only way that trehalose works to enhance autophagy by macrophages?

Cellular stress signals sent by macrophages amplify neuroinflammation, provide novel drug targets for MS therapy

The decreased protection in IgG1 - deficient mice correlates with less efficient bacterial opsonization and uptake by macrophages, and this reflects the low binding of outer membrane protein OmpD - specific IgG2a to the bacterial surface.

When this process starts, the damaged muscle fibers are broken down by lysosomal proteases, free radicals and many other compounds released by the macrophages.

These lipids get oxidized and are consumed by macrophages, creating a «fatty streak», which can be found as early as teenage years [28].

The study shows that test subjects with wheat germ extract in their diet have increased TNF secretion by the macrophages and stimulating NK cell activity (Natural Killer cells).

In the lymph nodes, «B» type lymphocytes, through their derivative «plasma cells», make antibodies to the antigens brought by the macrophages (humoral immunity); and «T» type lymphocytes prepare themselves to attack the foreign antigens (cellular immunity).

Takano T, Azuma N, Satoh M, Toda A, Hashida Y, Satoh R, Hohdatsu T. 2009 Neutrophil survival factors (TNF - alpha, GM - CSF, and G - CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions.

The microscopic description is usually something like this: hemotoxylin and eosin - stained sections of the mass and adjacent tissue contained irregular lobules of fine mineralized material cuffed by macrophages and multinucleated giant cells....

Not exact matches

The tattooing process works by injecting ink into the skin, which stimulates an immune response in which cells called «macrophages» move into the area and «eat up» the ink.

I aspire to be the utmost dangerous pathogen to be sought out, eaten up, spit out, and ejected by every available macrophage:D.

These growth modulators are produced either by the epithelial cells of the mammary gland or by activated macrophages, lymphocytes (mainly T cells), or neutrophils in the milk.

Macrophages were dry - fractured by touching the cell surface with cellophane tape after critical point drying to reveal intracellular bacteria.

Ferumoxytol leaks out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.

NF - kB enables cancer cells to survive the pro-apoptotic influence of tumor necrosis factor that is released by tumor infiltrating macrophages;

By «plugging in» to the cardiomyocytes, macrophages help the heart cells receive the signals and stay on beat.

For the research, the scientists used the platform to target colon macrophages in order to reduce inflammatory symptoms caused by Inflammatory Bowel Disease (IBD) in mouse models.

Onion A increases anti-tumor immune response by inhibiting the immune suppression actions of macrophage and myeloid derived suppressor cells (MDSC).

By analyzing chemical changes of the IRS - 2 protein in immortalized cultures of human white blood cells, it determined that IRS - 2 appeared in two different forms — «on,» which allows the signal to pass through, and «off,» which stops the signal from activating the cells into M2 macrophages.

Phagocytosis is a process by which white blood cells called macrophages digest cellular debris and foreign bodies and particles.

A final series of tests confirmed that toxic compounds generated by antibodies kill bacteria without any help from other immune cells, like macrophages.

By targeting this switch with tiny molecules, researchers could deny the macrophages calcium and prevent inflammation — even in the brain.

By contrast, when the team treated the mice with radiation plus a CCL2 - blocking antibody, the tumors» recruitment of monocytes and macrophages was sharply reduced, and the tumor growth was slowed more dramatically.

An early - stage clinical study by another institution, published in the Lancet Oncology in May 2016, combined chemotherapy with an experimental drug that blocks CCR2, a receptor on monocytes and macrophages whose activation stimulates these cells to infiltrate tumors.

This is important as one of the reasons tumour cells are so pernicious is that they are able to hide from the body's immune system, by hijacking macrophages.

By changing the macrophages» metabolism, we actually set up a «glucose competition» between the macrophages and the tumor's blood vessels.

A team led by professor Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer.

Consequently, they discovered that by blocking Nrp1, macrophages were no longer able to migrate inside hypoxic regions in the tumor.

Green tattoo pigment is taken up by dermal macrophages (left).

«Tattoo removal can be likely improved by combining laser surgery with the transient ablation of the macrophages present in the tattoo area,» says Malissen.

Over the following few weeks, these cells are replaced by new macrophages derived from precursor cells known as monocytes.

The team determined that the dead macrophages release the pigment into their surroundings, where, over the following weeks, it is taken up by new, monocyte - derived macrophages before it can disperse.