Sentences with phrase «pharmaceutical drug trials»

Not exact matches

In December, Tehrani signed a deal with GlaxoSmithKline that will allow the pharmaceutical giant to test at least four of its drug candidates on a Zymeworks - designed platform, which combines a computer simulation with a way of engineering protein molecules and allows products to be refined before they move to expensive clinical trials.

Nedlands - based pharmaceutical company PharmAust has raised about $ 3.1 million in an oversubscribed placement to fund clinical trials for its cancer drug.

John Rountree, managing partner at Novasecta, discusses the fallout of a disappointing breast cancer drug trial for pharmaceutical firm Roche.

Today, more than 15,000 people have taken Lactagen, an over-the-counter derivative of the formula Ritter cooked up, and his company, Ritter Pharmaceuticals, is about to launch trials for a prescription drug to treat lactose intolerance — an endeavor that can cost upward of $ 50 million before the FDA gives its OK.

The Food and Drug Administration (FDA) has given Alnylam Pharmaceuticals the green light to relaunch clinical trials of its treatment for the bleeding disorder hemophilia after pausing the studies after a patient death.

Deals with pharmaceutical makers to package the Biojector 2000 with specific drugs — including those being used in clinical trials — give it a clear advantage over some competing devices, says Bioject CEO Jim O'Shea.

Headquartered near Boston, Massachusetts, Parexel provides a range of services to the pharmaceutical industry, ranging from drug development and regulatory consulting to clinical pharmacology, clinical trials management and reimbursement.

However, in very rare circumstances, Ionis Pharmaceuticals is able to make an experimental drug that we are developing available for patients outside of a traditional clinical trial under an expanded access protocol, sometimes referred to as a treatment protocol.

Achillion Pharmaceuticals (ACHN) is another frontrunner, with three experimental drugs in clinical trials.

No. 1: Medical marijuana laws are passed, but GW Pharmaceuticals shares will continue to drop Admittedly, this is a new spin on my 2015 prediction that shares in marijuana drug developer GW Pharmaceuticals plc (NASDAQ: GWPH) would fall because of trial failures.

The company has deep expertise in pharmacology and the pharmaceutical commercialisation process, including clinical trials, drug development and optimisation, regulatory liaison and licensing / M & A plans.74

Merck Pharmaceuticals (also manufacturers of the Follistim Pen) selected Pacific Fertility Center as one of about 35 study sites located in the United States to participate in this investigational drug trial in the largest multi-center IVF trial ever undertaken.

Several potential jurors at the federal securities fraud trial of Martin «Pharma Bro» Shkreli were excused after telling the judge they couldn't be impartial toward the flamboyant former pharmaceutical CEO because of his notoriety for raising the cost of a life - saving drug 5,000 percent.

The Rolls Royces of science experiments — relatively low risk and decent payoff — are Phase I drug trials conducted by pharmaceutical companies.

And in several large - scale pharmaceutical trials, drugs specifically designed to elevate HDL had no effect on heart disease risk.

Almost all of the trials included in the meta - analysis were funded in part by pharmaceutical companies, and some of the meta - analysis's co-authors have received honoraria from drug companies, too.

The initial data showed enough promise to convince Roche to license the drug from California - based Ionis Pharmaceuticals, which sponsored the recent Huntington's trial.

The Rose Garden award ceremony for Kelsey followed in August, and an omnibus bill tightening regulations on the pharmaceutical industry and drug trials passed the Senate two weeks later.

Respondents in this year's survey pointed to five main causes of the field's less than favorable reputation: drug and product recalls such as the withdrawal of Avandia; safety issues such as the discovery of problems with raw material from China used in medical products; scandals, including evidence that pharmaceutical companies have failed to release data from trials whose results cast doubts on their drugs» safety and efficacy; lawsuits brought against companies that failed to warn patients of problems with their products; and ethical issues such as kickbacks for physicians promoting specific medications.

In March, researchers, in collaboration with the pharmaceutical company Ultragenyx, completed the first part of a Phase III clinical trial in adults with XLH — the final test of a drug before federal approval.

Three studies presented at the American Epilepsy Society's 69th Annual Meeting in Philadelphia highlight emerging efficacy and safety data of Epidiolex, a pharmaceutical liquid formulation of cannabidiol, which is currently undergoing U.S. Food and Drug Administration (FDA) authorized Phase 3 pivotal clinical trials in the United States and across the globe by GW Pharmaceuticals.

The British Heart Foundation has pledged # 1 million towards the trial, and the pharmaceuticals industry has offered to give drugs worth # 10 million.

The trial using medicines produced by Egyptian drug manufacturer Pharco Pharmaceuticals was run by DNDi and co-sponsored by the Malaysian Ministry of Health, in ten sites in Malaysia and Thailand.

They cite the example of TransCelerate BioPharma, a group of 10 major pharmaceutical companies that came together to share and direct resources toward selected priorities in order to improve the efficiency of drug development, such as clinical trial site qualification standards.

Great Britain, no slacker in the war on drugs, takes this approach: the government has authorized a pharmaceutical firm to grow different strains of marijuana for clinical trials.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

Goldhammer points out that all clinical trials are reviewed by the Food and Drug Administration and by the journals that publish them and that pharmaceutical companies require the researchers they support to state their sources of funding.

Last month, a German pharmaceutical company enrolled the first volunteer into what is intended to be a 300 - person randomized clinical trial testing an experimental drug to prevent psychosis in those at extremely high risk.

For example, pharmaceutical companies could conduct predictive screenings for drugs before clinical trials and determine which groups of patients would experience side effects and which ones wouldn't.

Not for nothing have share prices in pharmaceuticals reacted like apoplectic kangaroos to each whiff of a promising AAMI drugs trial.

The third millennium will see pharmaceutical - driven clinical drug trials in India as a «sunrise industry.»

Clinical researchers can end up anywhere from academia, where posts are based at university medical school research units or at hospital research units, to pharmaceutical or biotech companies, or in contract research organisations (CROs), which carry out clinical trials for drug or biotech companies.

Though Shkreli is best known for hiking the price of a decades - old drug by 5,000 percent when he led Turing Pharmaceuticals, this trial related to an entirely different matter: Ponzi - like fraud.

Afferent Pharmaceuticals today announced publication of results from a Phase 2 clinical trial demonstrating that the company's novel drug candidate, AF - 219, reduced daytime cough frequency by 75 % compared to placebo in patients with treatment - refractory chronic cough.

He will assemble a group of people to voluntarily try an existing drug for a new application before a pharmaceutical company embarks on a bigger, more costly human trial.

According to Next Wave's guest Tooling Up columnist Chandra Louise, «the membership directory of the Drug Information Association might be an excellent place to start looking for the name of a clinical trials manager in a pharmaceutical company.»

The British pharmaceutical company GW Pharmaceuticals is currently testing the drug, which is delivered as a mouth spray and called Sativex, in clinical trials.

The company that developed the drug, Tekmira Pharmaceuticals of Burnaby, Canada, and the Wellcome Trust, which sponsored the trial, announced today that they would not enroll any more patients because the trial had reached «a predefined statistical endpoint.»

Evidence supporting this view comes from medical trials that show placebo drugs may work as well as pharmaceuticals in providing relief.

Activists often slam large pharmaceutical companies for failing to develop drugs that are of critical importance to the developing world.Andrew Witty, GlaxoSmithKline's youthful chief executive, gave those critics pause yesterday in a speech to the Council on Foreign Relations in New York City.Witty promised to sell the company's malaria vaccine that is in late - stage clinical trials in Africa for no more than a 5 percent profit.

«This is the first instance I am aware of where an academic drug discovery group moved a molecule designed to hopefully treat a chronic brain disorder all the way from early discovery to human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNdrug discovery group moved a molecule designed to hopefully treat a chronic brain disorder all the way from early discovery to human trials without there being, at some point along the way, a pharmaceutical partner,» said P. Jeffrey Conn, Ph.D., Lee E. Limbird Professor of Pharmacology in the Vanderbilt University School of Medicine and director of the Vanderbilt Center for Neuroscience Drug Discovery (VCNDrug Discovery (VCNDD).

The work should be significant for pharmaceutical companies that design drugs through painstaking processes and at great cost by eliminating some of the trial and error in identifying new sites on proteins that could be more easily manipulated to treat disease, said Rice biological physicist José Onuchic.

Promote human clinical trials of repurposed drugs, in collaboration with medical centers (like UC San Francisco) and pharmaceutical companies in the US and abroad.

Illustrating the tricky path current Alzheimer's research faces, the study was published literally hours after giant pharmaceutical company Merck announced the cancellation of a Phase 3 clinical trial surrounding a drug that targets the exact same enzyme.

iBET's infrastructure comprises 16 laboratories fully equipped with state - of - the - art technology (70 m2 each), including a BSL2 laboratory for working with viruses; a GMP Analytical Services Unit certified by the INFARMED (the Portuguese medicines authority, EMA Portuguese branch) and by DGAV (the Portuguese veterinary authority) for quality control and batch release of human and veterinary pharmaceuticals, biopharmaceuticals as well as experimental new drugs; a GMP Mass - Spectroscopy Unit that provides state - of - the - art MS services to the scientific community and Industry; a 2600 m2 bio-pilot plant supporting production and purification of proteins ATMPs and vaccines from bench top to 300 L scale and privileged access to GeniBET Biopharmaceuticals, an iBET spin - off producing ATMPs under cGMP certification for phase I / II / III clinical trials.

Sonia and Eric already are talking to pharmaceutical companies that may be involved in running human trials in the future, and have requested a meeting with the Food and Drug Administration to talk about what a trial should involve.

GW Pharmaceuticals conducted three randomized, double - blind, placebo - controlled trials with the drug.

But testing two experimental drugs in a clinical trial is forbidden, and even if it weren't, it would be tricky to get two pharmaceutical companies to hop into human testing together.

Researchers said the ability to record those two functions would be useful to pharmaceutical companies because it could alert drug manufacturers to cardiac problems caused by a drug early in the process before reaching the clinical trial stage.

However, with few exceptions, the stem cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more interest in the use of hiPSCs as a source of large, pure populations of specific somatic cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses of stem cells and their derivatives.