Sentences with phrase «pharmacogenomic drug»

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The current method of prescribing medication now sometimes includes a pharmacogenomic approach, but researchers recognize the limitation of this approach in predicting a response to a particular drug and dosage combination.

Pharmacogenomics — Personalized Drugs, Personalized Careers Even in one of the worst years ever for employment in the biotech industry, according to Jim Kling, pharmacogenomics trainees find themselves with abundanPharmacogenomics — Personalized Drugs, Personalized Careers Even in one of the worst years ever for employment in the biotech industry, according to Jim Kling, pharmacogenomics trainees find themselves with abundanpharmacogenomics trainees find themselves with abundant opportunities.

From the very first collaborations with companies doing pharmacogenomic analyses on new drugs, he has had to abide by strict agreements of confidentiality.

That's why some AD researchers are turning to pharmacogenomics: the study of how genes influence the way we respond to drugs.

As a member of their scientific advisory boards, he helps the study directors design the pharmacogenomic portion of new clinical drug trials.

«What most pharma look to me for is my 10 years of experience in pharmacogenomic clinical drug trial design and result interpretation,» he explains.

And most of the time, pharmacogenomics is one of a series of tools — albeit a crucial one — that researchers use to investigate how patients respond to drugs, and the mechanisms of drugs and drug interactions.

He also analyzes the pharmacogenomic data and their potential impact on drug approval and commercial sales.

Pharmacogenomics — the study of how genes affect responses to drugs — is becoming more important in drug - development research and clinical trials, with a view toward decreasing side effects and increasing the efficiency and efficacy of drugs in patients with the right genetic profiles.

Drug companies were much in evidence at the convention, and if there is one area of genomics that has attracted a critical mass of believers, it's pharmacogenomics.

It also alludes to the complex phenotypes and rare drug outcomes resulting from rare pharmacogenomic variants.

Pharmacogenomics aims to rationalize drug use by minimizing drug toxicity and / or by increasing...

The DrugeVar database, an online database triangulating drugs with genes and pharmacogenomics...

Themed «Rare Genomics: Genomics of Rare Diseases, Rare Cancers and rare Drug Outcomes», this international scientific event will revolve around the application of the most important disciplines of Genomic Medicine, such as Genome discovery, informatics, Public Health, and drug design in Rare Diseases, Cancer and PharmacogenomDrug Outcomes», this international scientific event will revolve around the application of the most important disciplines of Genomic Medicine, such as Genome discovery, informatics, Public Health, and drug design in Rare Diseases, Cancer and Pharmacogenomdrug design in Rare Diseases, Cancer and Pharmacogenomics.

Lastly, this part summarizes the various regulatory aspects of pharmacogenomics and their role in drug development.

Results of this study has shown that there is a significant inter-population variability, as far as pharmacogenomic biomarker allele frequency is concerned, which has a direct impact on the rationalization of drug use at a population level.

The process they have followed in order to gather the specific information was to extract from the published literature all pharmacogenomic biomarkers that relate to the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) approved drugs with pharmacogenomic information in their label and make them available in a database that triangulates between drugs, genes and pharmacogenomics biomarkers.

Members of the Genome Informatics Working Group have recognized the need to provide a comprehensive resource for pharmacogenomic biomarkers information for those drugs that are approved by regulatory authorities.

A pharmacogenomic method for individualized prediction of drug sensitivity.

Bringing together a patient's genetic test results and relating those to clinical, published knowledge about pharmacogenomic relevance, explained O'Donnell, the portal gives physicians instant access to drug risks or benefits specific to an individual's genotype.

Pharmacogenomics, the study of how an individual's genetic variations impact the response to drugs, has emerged as an essential tool to optimize therapy and minimize the risk of adverse effects.

An online resource triangulating drugs with genes and biomarkers for clinical pharmacogenomics.

It is expected that pharmacogenomics is most likely cost - effective, since it reduces the incidence of adverse drug reactions, which can reciprocally reduce healthcare expenditure at the national level.

One of the most important prerequisites of the successful implementation of pharmacogenomics into the clinic is the increase of the general public's awareness over the benefits of pharmacogenomics in rationalising drug use.

Pharmacogenomics of NAT2 influences Oral Anti Tuberculosis Drug Induced Hepatotoxicity in Indonesia

Clinical application of pharmacogenomics knowledge will result in less «trial and error» prescribing and more efficacious, safer and cost - effective drug therapy.

The Sections aims are, to promote the exchange of pharmacogenetic knowledge by organization of symposia and workshops in the field of pharmacogenetics and genomics, to evaluate the clinical impact of pharmacogenetics, to assist with the development and maintenance of drug - related pharmacogenetic databases and to create a population based biobank to conduct translational research in clinical pharmacogenomics.

Hakonarson H and Stefansson K Role of pharmacogenomics in drug development Drug Development Research 2004 62 (2): 86 drug development Drug Development Research 2004 62 (2): 86 Drug Development Research 2004 62 (2): 86 - 96

-- search and browse through established pharmacogenomic gene - variant - drug - metabolizer status associations; (2)

For example, it is used to identify correlations between gene sequences and diseases, to predict protein structures from amino acid sequences, to aid in the design of novel drugs, and to tailor treatments to individual patients based on their DNA sequences (pharmacogenomics).

Fifty - one of the 71 cardiovascular drugs they focused on (71.8 percent) had detectable pharmacogenomic effects.

«I have long been familiar with the common variations in response to drugs, but, like most physicians in my specialty, I had limited knowledge of the pharmacogenomics behind it, or the ability of this information to predict a problem.»

Pharmacogenomics Knowledge Base; curated and annotated information regarding the effects of human genetic variations on drug response.

To help physicians make better - informed clinical decisions, researchers from the University of Chicago and Stanford University combed through scientific literature on the pharmacogenomics of 71 leading cardiovascular drugs and compiled summaries, published in the June issue of the Mayo Clinic Proceedings.

With its uniquely comprehensive population data, deCODE is turning research on the genetic causes of common diseases into a growing pipeline of products and services — in pharmaceuticals, gene and drug discovery, DNA - based diagnostics, pharmacogenomics, bioinformatics, and clinical trials.

To provide insight on the utility and practicality of implementing a pharmacist - driven pharmacogenomics program in a community pharmacy or primary care setting and to provide a clinical update on common drug - gene implications using clinical case vignettes.