Pharmacogenomic testing refers to a type of medical test that helps doctors identify how a person's genes might respond to certain medications. It can guide doctors to prescribe the most effective and safe medications for each individual, based on their genetic makeup.
Full definition
The U-PGx consortium will address major challenges and obstacles for implementation
of pharmacogenomics testing in patient care, taking into account the diversity of healthcare systems and citizens across Europe.
This working group is currently evaluating the impact of
pharmacogenomic testing in reducing the healthcare costs of anticoagulation therapy and treatment for nicotine addiction, while these projects will soon be expanded in various healthcare systems to assess whether pharmacogenomics can indeed reduce the overall costs of these treatment modalities.
This project indicated that not only a vast number of novel potentially functional variants in a total of 231 pharmacogenes was identified but also demonstrated the value of whole - genome sequencing
for pharmacogenomic testing by capturing over 18,000 variants per individual in these pharmacogenes.
In the meantime, we are working to
develop pharmacogenomic tests that can help to optimize the benefit to patients of currently available treatments.»
However, despite the major advances in pharmacogenomics and several commercially
available pharmacogenomics tests, its application in routine patient care remains very limited.
With the availability of a
simple pharmacogenomic test, doctors may be able to prescribe the most beneficial medicines for their patients without a costly and time - consuming process of trial and error.
With thousands of
pharmacogenomic tests under development and many becoming available for clinical use, it is becoming increasingly important to understand the costs and benefits of these tests so that their potential for widespread use can be critically evaluated in ways that optimize their usefulness.
In this role, he leads an initiative exploring the benefit of incorporating
broad pharmacogenomic testing into routine clinical practice for patients with any type of disease.
Proponents of personalized medicine were thankful for several developments that show this trend is picking up speed: CVS followed Medco's example in
expanding pharmacogenomic testing, while biotech and pharma companies, as well as the National Cancer Institute, stepped up their investment in the field.
Pharmacogenomics testing Traveled to various offices in the Atlanta area to perform pharmacy and specimen operations Observe and collect direct urine samples, random and scheduled.
The goal of
pre-emptive pharmacogenomics testing is to take into account the impact of each individual's genetic variants when selecting therapy thus providing personalized medicine.
This Working Group has undertaken a project to provide proof - of - principle of the use of whole - genome sequencing
for pharmacogenomic testing, by resequencing with high coverage, of almost 500 human genomes, mostly from Caucasian populations.
Economic Modeling: Our economic modeling core, led by Dr. Ann Wu, uses a variety of modeling approaches to project the medical and financial consequences of genomic medicine, including the use
of pharmacogenomic testing to inform medication choices and the use of sequencing as an adjunct to standard newborn screening.
This part also refers to the analytical methods used in
pharmacogenomic testing.
Pharmacogenomic testing may help identify subsets of the population who carry genetic variants that may alter psychotropic response to specific antidepressants.
The new model of personalised medicine through pre-emptive
pharmacogenomics testing will be conducted at a large scale in seven existing European health care environments in the Netherlands, Spain, UK, Italy, Austria, Greece, and Slovenia.