Few in vitro studies have provided bioavailability and
pharmacokinetic data differentiating the most optimally absorbed glucosamine formulation in canines.»
Extralabel use in food animals necessitates an extralabel withdrawal interval to be assigned by the attending veterinarian on the basis of information on the species, dose, route and frequency of treatment in conjunction with available scientific
pharmacokinetic data.
(6) Based on what is known about the behavior of the antibody and the available
pharmacokinetic data, Prothena CEO Gene Kinney has stated (albeit without presenting modeling to support the assertion) that «we would expect to fully saturate that pathological load [of aggregated AS] in patients with Parkinson's disease.»
«
The pharmacokinetic data by Dr. Smith and colleagues suggests that lithium salts other than the commonly used lithium carbonate may have a broader therapeutic window and potentially fewer side effects.
Not exact matches
In conclusion, anthelminthics poorly fulfill the preconditions of a specific mode of anticancer action and availability of
pharmacokinetic and pharmacodynamic
data for a favorable repurposing as anticancer drugs.
Approval may be accelerated by knowledge of previous preclinical and clinical
data on
pharmacokinetics, side effects and regimens [5, 87, 88].
The
data collected to date suggest that J147 has good
pharmacokinetic and safety profiles.
Because the long - term use of VPA in the clinical setting amassed
pharmacokinetics and safety
data, it is rational to test VPA in allogeneic BMT patients in combination with standard GVHD prophylaxis or treatment.
Due to the sex - related disparities in
pharmacokinetics and bioavailability results reported by different authors (Soldin, Chung, & Mattison, 2011; Soldin & Mattison, 2009), the choice of a single genus was chosen to avoid a high dispersion in the
data, and the availability of healthy young adult female volunteers for the study.