Safety, tolerability, and
pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267.
Importantly, due to their limited
pharmacokinetic interactions with other agents, DCV+SOF was able to work effectively across a broad range of concomitant combination antiretroviral therapy (cART) regimens without compromising HIV virologic control (98 % of patients were on cART).
Not exact matches
Pharmacokinetic variability, hepatic metabolism of drugs, clearance with renal elimination, drug
interactions (8) http://www.cnn.com/2007/HEALTH/conditions/09/26/unapproved.drugs/index.html NEW YORK (CNN)-- Every year, doctors write approximately 65 million prescriptions for drugs not yet approved by the U.S. Food and Drug Administration, the federal agency that regulates prescription drugs.
The
pharmacokinetics of a bioactive will greatly depend on the age, genetics / metabolic capacity, nutrientgene
interaction, body mass index, health condition and food matrix.