Sentences with word «pharmacologic»

This Finnish nationwide cohort study examines the comparative effectiveness of pharmacologic treatments in the prevention of rehospitalization in a nationwide cohort of patients with bipolar disorder.

«Although researchers have learned much about the effects of pharmacologic agents on Schlemm's canal as well as its local ultrastructure through electron microscopy, we know remarkably little about its formation, functional architecture and specialized molecular features,» says John.

High concentrations of vitamin D2 in human milk associated with pharmacologic doses of vitamin D2.

They found that, in pharmacologic doses administered intravenously, ascorbic acid successfully killed cancer cells without harming normal cells.14 This is yet another example of cancer cells being vulnerable to acidity, as opposed to alkalinity.

There are no proven pharmacologic therapies for age - related hearing loss, but that may soon change.

The average cost of pharmacologic approaches was calculated at $ 250 for the intake consultation and a professional fee of $ 140 per consultation.

The study discovered that after half a year, minimal contact behavioral chronic migraine treatment was competitively priced with pharmacologic treatments making use of medications costing 50 cents or less daily.

University of Wisconsin A chemical - genetic library of human cell lines for evaluating pharmacologic inhibition of protein kinases

They stated that TMS holds promise as a physiologic biomarker in AD to identify therapeutic targets and monitor pharmacologic effects.

Residency programs encompass most veterinary clinical specialties as well as pharmacologic, pathologic, and toxicologic fields.

In addition, inhibiting this enzyme represents a unique therapeutic vulnerability in cancer stem cells with active inflammatory signaling that may respond to pharmacologic inhibitors of inflammation sensitivity or selective ADAR1 inhibitors that are currently being developed,» Jamieson said.

We examined the response of pharmacologic modulation of autophagy in an HPV mouse model of anal carcinogenesis.

Over the past 5 years, a number of new pharmacologic treatments for advanced melanoma have been introduced, including immunotherapy, targeted agents (BRAF and MEK inhibitors), and oncolytic viral therapy.

Pharmacologic manipulation of ob expression in a dietary model of obesity.

Moreover, large - scale screens in the C. elegans DMD model allowed identifying genetic and pharmacologic suppressors of dystrophin - dependent muscle degeneration; some of them positively impact mitochondrial functions or structure under stress conditions, or are involved in signaling pathways linked to mitochondria, and others are associated to proteostasis pathways such as autophagy, proteasome and Unfolded Protein Response (UPR).

High profits may be justified if novel products offer significant benefits to patients (thus producing indirect economic value through the patients» restored health) or if they represent significant pharmacologic advances over their predecessors — offering new mechanisms of actions and emblematic of high - risk research.

«Our findings suggest that water birth is a reasonably safe option for low - risk women, especially when the risks associated with pharmacologic pain management, like epidural anesthesia, are considered.»

There is no specific pharmacologic treatment for RAD or DSED patients.

«We wanted to use pharmacologic means to get the same effect as the gene variant,» says Alban Latremoliere, PhD, also of Boston Children's Kirby Center, who led the current study along with Woolf and Costigan.

In addition, nutraceuticals may help when combined with other pharmacologic interventions.

Symposia II: Personalized Exercise Prescription Based Upon Integrative Biology Experts will explore genetic, transcriptomic, phenotypic and pharmacologic considerations in identifying and predicting individual response to exercise regimens.

First off, it contains Dinotefuran which is a lot similar in pharmacologic action to Imidacloprid especially in the inhibition of nicotinic receptors in the flea nervous system.

There are several drugs which obviously do increase milk supply, and of course it is reasonable to assume that some plants and herbs might contain similar pharmacologic agents.

The brightest and wealthiest of my HIV «afflicted patients can hold out against its ravages by means of the most complicated of medical / pharmacologic regimens.

The AAP conference is currently the largest venue to debut in its exhibit hall the latest pediatric medical and pharmacologic products, services, resources, and technologies.

Medscape: What are the best resources for a clinician who needs to access information about a particular pharmacologic agent quickly, in the middle of a busy clinical day?

In the Pregnancy subsection, the Fetal Risk summary will provide a narrative description based on risk evaluations of human, animal, and pharmacologic data that describe the likelihood that a drug increases the risk for adverse developmental outcomes.

Large - scale genetic and clinical investigations are needed to clarify the effects of pharmacologic lowering of LDL - C and TG levels to gauge dysglycemic associations.»

A system for direct pharmacologic control of protein secretion was developed to allow rapid and pulsatile delivery of therapeutic proteins.

To overcome the structural flexibility of the β2AR and to facilitate its crystallization, we engineered a β2AR fusion protein in which T4 lysozyme (T4L) replaces most of the third intracellular loop of the GPCR («β2AR - T4L») and showed that this protein retains near - native pharmacologic properties.

«We found that high pharmacologic levels of the bioactive drug of interest can be achieved at the intestinal surface without systemic circulation of the drug,» Chung explains, so the drug can be administered without the threat of potential toxicities associated with exposure to kidney, liver and brain tissue.

«Anti-aging gene identified as a promising therapeutic target for older melanoma patients: Pharmacologic activation of anti-aging gene with anti-diabetic drug could be used as adjuvant therapy for older melanoma patients who have developed resistance to targeted therapy.»

«There is an urgent need for a safe pharmacologic therapy that can prevent of regress the progression of liver damage.

«There are more than five million Americans living with Alzheimer's, and yet there are few promising pharmacologic treatment options for this progressive disease,» says Dr. Ponce.

Both possess novel — although different — pharmacologic attributes.

«We show for the first time that selective pharmacologic inhibition of the 12 / 15 - lipoxygenase enzyme rescues the entire AD - like phenotype,» Praticò said.

«While most pharmacologic treatment for depression target monoamine systems, such as serotonin, dopamine and norepinephrine, this intervention targets the parasympathetic and gamma aminobutyric acid system and provides a new avenue for treatment.»

To date, there are no approved pharmacologic strategies to reduce liver fat.

«Our study found that statins, in addition to conventional venous thromboembolic pharmacologic therapy, significantly reduced the event of VTE in the post-operative period for patients undergoing elective total hip and knee replacements,» said Philadelphia - based orthopaedic surgeon and lead study author Katharine T. Criner, MD. «The relative risk of VTE with use of statins was reduced by 48 percent.

The article, published in CMAJ (Canadian Medical Association Journal) looks at the latest pharmacologic research as well as disease - modifying agents and the benefits and risks of various treatments.

In the study, the research team presented a novel pharmacologic candidate that alleviates age - related degenerative joint conditions, such as osteoarthritis (OA) by selectively destroying SnCs.

He and his colleagues employ pharmacologic, brain imaging, epidemiologic, genomic, and cell model approaches to study schizophrenia and bipolar disorder, in particular.