The current clinical trial was somewhat different to the transplantation trial in that treatment effect was an immediate
pharmacologic effect that disappeared once the drug was withdrawn, suggesting plasticity was less important, but the mechanism of recovery is unclear.
Not exact matches
This information is important not only to protect nursing infants from untoward
effects of maternal medication but also to allow effective
pharmacologic treatment of breastfeeding mothers.
If a
pharmacologic or chemical agent does not appear in the tables, it does not mean that it is not transferred into human milk or that it does not have an
effect on the infant; it only indicates that there were no reports found in the literature.
Large - scale genetic and clinical investigations are needed to clarify the
effects of
pharmacologic lowering of LDL - C and TG levels to gauge dysglycemic associations.»
The researchers demonstrated that blocking the PGD enzyme genetically or with a
pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no
effect on normal cells or peritoneal pancreatic cancer controls.
«We wanted to use
pharmacologic means to get the same
effect as the gene variant,» says Alban Latremoliere, PhD, also of Boston Children's Kirby Center, who led the current study along with Woolf and Costigan.
Differential
effects of
pharmacologic and genetic modulation of NMDA receptor activity on HIV / gp120 - induced neuronal damage in an in vivo mouse model.
Phase I Trials initial studies to determine the safety and
pharmacologic actions of drugs in humans, and the side
effects associated with increasing doses; in some cases can also be used to gain early evidence of effectiveness.
Parents concerned about the side
effects and long - term use of conventional medications are increasingly seeking alternatives to
pharmacologic treatment.
Herbalists believe that whole plants provide a broad spectrum of desirable
effects, from specialized nutrition (herbs contain vitamins and minerals that drugs do not) to synergy of the various components, which may allow lower doses of
pharmacologic ingredients to be used.
According to Lilly, Canada now requires regulatory - type testing before a patent can be filed — which obviously has a chilling
effect / is not very practical, and discriminates in the area of therapeutic /
pharmacologic patents.