Sentences with phrase «pharmacologic inhibitors»
The researchers demonstrated that blocking the PGD enzyme genetically or with a pharmacologic inhibitor reversed the epigenetic reprogramming and malignant gene expression changes detected in distant metastases, and also strongly inhibited their tumor - forming capacity, with no effect on normal cells or peritoneal pancreatic cancer controls.
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«Our results suggest that pharmacologic targeting of the CB with a CSE inhibitor, such as L - PAG, might prevent apneas.»
«Nonetheless,» they conclude, «pharmacologic modulation of the CB chemoreflex by an inhibitor of H2S synthesis, as shown in the present study, has the potential to significantly improve the clinical management of sleep apnea.»
Competitive pathway analysis implicated the biological processes of neurogenesis and synaptic regulation, as well as the gene targets of two pharmacologic agents: cinnarizine, a T - type calcium channel blocker, and LY97241, a potassium channel inhibitor.
Over the past 5 years, a number of new pharmacologic treatments for advanced melanoma have been introduced, including immunotherapy, targeted agents (BRAF and MEK inhibitors), and oncolytic viral therapy.
Fluoxetine is a highly selective serotonin reuptake inhibitor thereby potentiating the pharmacologic activity of serotonin.