Sentences with phrase «pharmacological agent in»

Curcumin is the active ingredient and primary pharmacological agent in turmeric.

Curcumin, the ingredient in turmeric that is responsible for its golden colour, is thought to be the primary pharmacological agent in turmeric, and has important antioxidant, anti-inflammatory, and healing properties.

Not exact matches

It's used in cooking utensils, as described above, as well as in pharmacological agents like antacids and antiperspirants.

New avenues of research could include the effects of reducing environmental stress, as well as whether pharmacological agents might be able to reverse the genetic alternations in vulnerable children before the disorder develops.

Specifically, the Mount Sinai study was designed to test whether pharmacological compounds designed to block the function of XPO1 / CRM1 could stop disease progression in mouse models that exhibit some of the characteristics of MS. Researchers found that two chemical agents (called KPT - 276 and KPT - 350) prevented XPO1 / CRM1 from shuttling cargo out of the nucleus of nerve cells, which protected them from free radicals and structural damage.

The proteins pump pharmacological agents from the «brain side» to the «blood side» in the same way as in the human blood - brain barrier.

We are now in the process of studying the proteins in the blood - brain barrier that accept pharmacological agents instead of throwing them out.

If we can combine a beneficial substance which the brain needs with a so - called «absorber protein», we will in the long term be able to smuggle pharmacological agents across the blood - brain barrier.»

Although it is standard practice in reputable pharmacological papers to publish dose - response curves for any proposed agent, the smart drug literature is remarkably coy on this point.

In the research, Rieger treated the zebrafish with pharmacological agents that reduce MMP - 13 activity, with the result that skin defects were improved and chemotherapy - induced nerve damage was reversed.

After receiving a master degree in Biotechnology at the University of Verona (Italy) in 1998, I joined the neuroscience centre of GlaxoSmithKline (GSK), a large research - based pharmaceutical company based in Verona (Italy) and Harlow (UK), where I pioneered the use of functional magnetic resonance imaging (MRI) to describe the neural substrates modulated by pharmacological agents, a line of research that I also pursued to obtain a PhD degree in biomedical imaging with the University of Verona.

«With the appropriate pharmacological agent, it could be likely that we could prevent the heart damage often seen in some forms of muscular dystrophy,» said Campbell.

Title: Quantifying the attenuation of the ketamine pharmacological magnetic resonance imaging response in humans: a validation using antipsychotic and glutamatergic agents Author: O. M. Doyle et al..

Langmuir 29 (35), 10973 - 10979 (2013) «Reduced limbic metabolism and fronto - cortical volume in rats vulnerable to alcohol addiction» A. Gozzi, F. Agosta, M. Massi, R. Ciccocioppo, and A. Bifone NeuroImage 69, 112 - 119 (2013) «Polymeric nanocarriers for controlled and enhanced delivery of therapeutic agents to the CNS» M. Gagliardi, G. Bardi and A. Bifone Theraputic Delivery, 3 (7), 875 — 887 (2012), doi: 10.4155 / TDE.12.55 «Neuromapping techniques in drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the rat»

Freitas et al (2011) performed a systematic search of all studies using non-invasive stimulation in Alzheimer's disease (AD) and reviewed all 29 identified articles; 24 focused on measures of motor cortical reactivity and (local) plasticity and functional connectivity, with 8 of these studies assessing also effects of pharmacological agents, and 5 studies focused on the enhancement of cognitive function in AD.

«Deficient neuron - microglia signaling results in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic iron oxide nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.

The 1985 edition of Goodman and Gilman's The Pharmacological Basis of Therapeutics states that «the use of these agents (i.e., androgens) does not cause an increase in muscle bulk, strength, or athletic performance even when phenomenally large doses are used.

In one representative country, chronic pain takes up one - fifth of the entire health care expenditure, whereas in another it is three times as costly as all types of cancer together.59 One strategy which remains unexplored and could yield important insights is to combine a ketogenic diet with a known hypoalgesic pharmacological agent (e.g. amitriptyline) and note additive or synergistic effects, as have been noted for seizure control but only for some drugs.In one representative country, chronic pain takes up one - fifth of the entire health care expenditure, whereas in another it is three times as costly as all types of cancer together.59 One strategy which remains unexplored and could yield important insights is to combine a ketogenic diet with a known hypoalgesic pharmacological agent (e.g. amitriptyline) and note additive or synergistic effects, as have been noted for seizure control but only for some drugs.in another it is three times as costly as all types of cancer together.59 One strategy which remains unexplored and could yield important insights is to combine a ketogenic diet with a known hypoalgesic pharmacological agent (e.g. amitriptyline) and note additive or synergistic effects, as have been noted for seizure control but only for some drugs.60

A wide variety of pharmacological agents such as corticosteroids are known to be diabetogenic in people.