Sentences with phrase «pharmacological inhibitors»
"Pharmacological inhibitors" refers to substances or drugs that are used to block or control the activity of specific enzymes, proteins, or biological processes within the body, usually to treat certain diseases or conditions. These inhibitors work by interacting with the target and preventing its normal function, helping to regulate or stop a particular cellular or molecular process. Full definition
«Importantly, we found that blocking the actions of the endocannabinoids with pharmacological inhibitors of cannabinoid receptors in the periphery completely normalized food intake and meal patterns in western diet - induced obese mice to levels found in control lean mice fed standard chow.»
sciencedaily.com
«Our research shows that targeting cannabinoid receptors in the periphery with pharmacological inhibitors that do not reach the brain holds promise as a safe therapeutic approach for the treatment of overeating and diet - induced obesity,» said Nicholas V. DiPatrizio, an assistant professor of biomedical sciences in the School of Medicine, who led the research project.
It is now possible to determine the molecular structure of membrane proteins, previously difficult to characterize, offering better possibilities of developing pharmacological inhibitors for treating cancer and other diseases.
Other pharmacological inhibitors are being developed, which are more potent and / or are active against the emerging Gleevec / Glivec resistant BCR - abl clones in treated patients.
«These enzymes have also become increasingly important in disease development, particularly cancer, and efforts have intensified to develop specific pharmacological inhibitors targeting them.»
Microelectrode measurements and pharmacological inhibitor studies carried out on larval stages demonstrated that maintenance of alkaline gastric pH represents a substantial energy sink under acidified conditions that may contribute up to 30 % to the total energy budget.
Fortunately, there are pharmacological inhibitors of the enzyme that produces these fatty acids.
In their study, the researcher exploited this central position of EZH2 to combat the cancer: They used a pharmacological inhibitor to suppress the activity of EZH2.
«A real problem in the field has been assigning good biomarkers, which would help to treat cancer patients with these pharmacological inhibitors, such as rapamycin.
I think it's really exciting that we showed that cancer cells deficient in these GATOR proteins are hypersensitive to this pharmacological inhibitor of mTOR, rapamycin.
Although SMYD2 was not previously considered a target for HIV, pharmacological inhibitors are already being developed against this enzyme due to its effect on various cancer tumors.