Sentences with phrase «pharmacological profile»

Unique pharmacological profiles of substances in the SARM class mean they have a different range of effects and androgenic binding ratios.

Studies in rodents found that our new CFTR inhibitor potently blocked enterotoxin - induced fluid secretion in vivo and exhibited a favorable pharmacological profile, suggesting that it may be a potential drug candidate for the symptomatic treatment of secretory diarrhea.

The novel triple reuptake inhibitor JZAD - IV - 22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties.

They note that a related compound with better pharmacological profiles than CLP257 was as effective in reducing pain in rats as an existing pain treatment called pregabalin, but it lacked the undesirable motor side effects that are often seen with that drug.

Specific targeting of neurotoxic side effects and pharmacological profile of the novel cancer stem cell drug salinomycin in mice.

Jordi Mestres, coordinator of the IMIM and UPF research group on Systems Pharmacology at the Biomedical Informatics Program (GRIB) states «With this study we have contributed to complementing the detection of these quite unstable fragments, with information on the mechanism of action of the drug, based on three aspects: similarity to other medicines, prediction of their pharmacological profile, and interference with specific biological pathways.

This development could find broad applications in pharmaceutical and agricultural industries, enabling medicinal chemists to tailor synthetic molecules with halogen substituents in order to improve their pharmacological profiles.

The role of academic scientists in this process has largely been to explain the genetic / cellular basis of diseases for identifying useful targets and provide new chemical and computational methods to improve the pharmacological profile of potential drugs.

Schütz K, Carle R, Schieber A. Taraxacum — a review on its phytochemical and pharmacological profile.