For example, in the 1960's,
pharmacology studies showed that a compound from the Pacific yew, Taxus brevifolia, had anti-cancer properties, but the quantities of the compound were too low for commercial purposes.
Not exact matches
And a recent
study in Regulatory Toxicology and
Pharmacology (vol 64, p 345)
shows that animal tests missed 81 per cent of the serious side effects of 43 drugs that went on to harm patients.
It was the first
study to
show that sleep can be manipulated with
pharmacology to improve memory.
A team headed by Hanns Ulrich Zeilhofer from the Institute of
Pharmacology and Toxicology at the University of Zurich did now reveal which inhibitory neurons in the spinal cord are responsible for this control function: As the
study published in the science journal Neuron
shows, the control cells are located in the spinal dorsal horn and use the amino acid glycine as an inhibitory messenger.
Thomas L. Kash, PhD, associate professor of
pharmacology and the lead author of the
study published in the journal Cell Reports, used mice to
show the effects of KORs on behavior.
Thomas L. Kash, PhD, associate professor of
pharmacology and the lead author of the
study published today in the journal Cell Reports, used mice to
show the effects of KORs on behavior.
«Our
study shows that genotyping of CYP2C19 could be of considerable clinical value in individualising doses of escitalopram so that a better all - round antidepressive effect could be achieved for the patients,» says Professor Magnus Ingelman - Sundberg at Karolinska Institutet's Department of Physiology and
Pharmacology who led the
study together with Professor Espen Molden.
Results of a
study published online this week at Nature
show that Carabin «acts like an internal brake to dial down the speed and intensity of an immune response so that it doesn't go too fast or too far, or careen out of control and attack healthy cells,» says Jun O. Liu, Ph.D., professor of
pharmacology, neuroscience and oncology at Hopkins.
a) In the subsection «Cell type - specific NMDA - R
pharmacology in cocaine - induced synaptic plasticity» we now more clearly introduce the Zweifel and Engblom
studies as well as the differences between them: both of which used genetic ablation of Grin1 over 1 week but
showed different results with respect to DA neuron synaptic potentiation, which was due to methodological challenges with AMP - R compensation.
According to a
study published in the British Journal of Clinical
Pharmacology, CBD benefits include being anti-inflammatory and anticonvulsant, and has been
shown to help treat epilepsy, anxiety, and brain inflammation.
A
study published in Toxicology and Applied
Pharmacology showed that the chemicals have been linked to endocrine disruption; parabens compete with estrogen for sites to attach throughout the body, thereby potentially affecting hormonal balance.