The first
phase of treatment for uncomplicated diabetes is called regulation.
In order to obtain consistent and predictable results, surgeons, restoring dentists, orthodontists and dental technicians should work as a team.This course will describe
all phases of treatment for those patients receiving osseointegrated implants in the aesthetics zone, from treatment planning phase to completion, emphasizing the importance of soft tissue management from the prosthetic end as well as fundamental laboratory communication tools.
Not exact matches
«Based on the results from these
Phase 3 studies, the combination
of bictegravir and FTC / TAF could represent an important advance in triple - therapy
treatment for a broad range
of HIV patients, and we look forward to submitting regulatory applications in the U.S. and EU this year.»
Tax laws are subject to change and the preferential tax
treatment of municipal bond interest income may be revoked or
phased out
for investors at certain income levels.
March 30, 2017 — Aura Biosciences Announces Initiation
of Phase 1b Clinical Trial and Receipt
of FDA Fast Track Designation
for AU - 011
for the
Treatment of Primary Ocular Melanoma
Cambridge, MA — March 30, 2017 — Aura Biosciences, a biotechnology company developing a new class
of therapies to target and selectively destroy cancer cells using viral nanoparticle conjugates, announced today that it has enrolled and dosed the first patient in its
Phase 1b clinical trial
of light - activated AU - 011, an investigational, first - in - class targeted therapy in development
for the
treatment of ocular melanoma, a rare and life - threatening disease.
The biotech specialist said that its updated
phase 2 data in a study
of its poziotinib candidate
treatment for non-small cell lung cancer resulted in a preliminary confirmed objective response rate and potential progression - free survival benefit in patients with the EGFR Exon 20 Mutant form
of the disease.
«DRRX has initiated dosing in a
Phase IIatrial
for DUR - 928 in the
treatment of primary sclerosing cholangitis.»
Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines
for the
treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a
Phase 1b...
ALKS 3831 is a
treatment for schizophrenia that avoids the side effects
of weight gain and metabolic problems that the incumbent drug has, and a
phase 3 trial
for it should read out in the fall
of 2018.
«During product development, we brought together researchers in both the health and culinary fields to ensure a thorough understanding
of a patient's needs during various
phases of treatment,» said Chet S. Rao, Ph.D., strategy and business manager
for the specialty foods group at Hormel Foods.
This package includes the four courses Tough Starts: Brain Development Matters, Tough Starts:
Treatment Matters, Tough Starts, Parenting Matters, Tough Starts: Family Matters and four recorded webinars: Four Things Adoptive Parents Need to Know About Child Development, Sensory Integration, Snack Play Love, and Tired
of Timeouts
for a total
of 9.0 credit hours
of training on topics required by Forever Bound Adoption
for Phase 2 - After Placement.
ERIE COUNTY, NY — The Erie County Department
of Environment and Planning Division
of Sewerage Management has announced that today is the official start
of construction
for Phase II
of the Rush Creek Interceptor Project, which will involve the construction
of sewers to collect wastewater from the Blasdell Wastewater
Treatment Plant, three pumping stations, and three existing sewer overflows in the Blasdell area.
«In an earlier
phase I clinical study, our group has shown that increasing the dose
of radiation delivered daily with high precision and using image guidance may offset the need
for chemotherapy in improving survival, and it may also improve quality
of life measures by reducing
treatment periods in half.
A
phase III clinical trial in hundreds
of people must be performed before the
treatment could be recommended
for smokers, and Dr. Yuan warned that while eating cruciferous vegetables, such as watercress and broccoli, is good
for people, they are unlikely to have the same pronounced effect as the extract.
In
phase I trials, researchers test a new drug or
treatment in a small group
of people
for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
The guideline includes recommendations
for appropriate use
of these medications through each
phase of treatment, as well as
for patient monitoring and follow - up.
They were interested in a
phase separation phenomenon that has been known
for around 50 years, but could neither be precisely observed nor understood until now: The microstructure
of nickel - based alloys changes under controlled ageing or heat
treatment and in the classical two -
phase microstructure new
phases are initially formed.
Phase I / II clinical trial results reported at the American Society
for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results
for investigational drug brigatinib against ALK + non-small cell lung cancer (NSCLC), with 58
of 78 ALK + patients responding to
treatment, including 50
of 70 patients who had progressed after previous
treatment with crizotinib, the first licensed ALK inhibitor.
The study was a randomized
phase II trial testing whether the addition
of local
treatment, in the form
of consolidative radiation therapy, to the standard
treatment of systemic therapy improved progression - free survival
for patients with limited metastatic NSCLC.
While lithium carbonate has been very effective
for the
treatment of mania in bipolar disorder, and credited
for reducing suicides in depressive
phases of the disease, patients who take lithium carbonate are often noncompliant because
of adverse effects, including hand tremor, diarrhea, vomiting, weight gain and decreased thyroid function.
If doctors knew how the brain structure
of a patient will change and reorganize during
treatment, they could determine the ideal times
for phases of stimulation and rest, thus improving
treatment efficiency.
«Despite its narrow therapeutic window and the emergence
of proprietary alternatives, U.S. FDA - approved lithium therapeutics are still regarded as the «gold standard»
for the
treatment of the manic
phase of bipolar disorder,» said study lead author Adam J. Smith, PhD, a neuroscientist at the Center
of Excellence
for Aging and Brain Repair, Department
of Neurosurgery, at USF Health.
Results from three
Phase III clinical trials (ION - 1, ION - 2 and ION - 3) evaluating the investigational once - daily fixed - dose combination
of the nucleotide analogue polymerase inhibitor sofosbuvir (SOF) 400 mg and the NS5A inhibitor ledipasvir (LDV) 90 mg, with and without ribavirin (RBV),
for the
treatment of genotype 1 chronic hepatitis C virus (HCV) infection have been presented at the International Liver CongressTM 2014.
Pembrolizumab is set to become a new option
for first line
treatment of patients with advanced lung cancer and high PD - L1 expression, according to the results
of the
phase III KEYNOTE - 024 trial presented at the ESMO 2016 Congress in Copenhagen and published in the New England Journal
of Medicine.
Trial # 6:
Phase I clinical trial and pharmacodynamic evaluation
of combination HCQ and doxorubicin
treatment in pet dogs treated
for spontaneously occurring lymphoma
«Since several BACE1 inhibitors are currently being evaluated in clinical
phase 3 trials
for the
treatment of Alzheimer's disease, the identification
of potential side effects will be
of great importance to ensure a positive clinical outcome,» said Dr. Jochen Herms, a Professor
of translational brain research at Ludwig - Maximilians - University Munich.
P: We found discodermolide [a drug from Discodermia, a sponge found in the Caribbean, the Bahamas, and the Gulf
of Mexico], and it's gone through
phase I clinical trials
for treatment of solid tumors such as ovarian, pancreatic, breast, colon, or lung cancers.
«First - line immunotherapy
treatment can improve survival
for subset
of lung cancer patients: Results
of phase III global clinical trial show that 75 percent
of stage IV lung cancer patients with both complex tumor mutations and PDL - 1 positive status respond to nivolumab.»
This study is the first
phase of a larger initiative to develop and pilot test Critical Time Intervention, a transitional assistance model
for individuals leaving residential substance abuse
treatment.
CROs tend only to be involved in one specific aspect
of the
treatment under trial or during one particular
phase so people working
for them see less
of the big picture.
«We are now waiting
for phase III results to confirm the favorable predictions
of this
treatment with cediranib.»
The shorter, safer and more effective antifungal drug regimen treats cryptococcal meningitis with a one - week combination antifungal regimen
of amphotericin B and flucytosine
for the initial induction
phase of treatment.
Results
of a
phase 2 study published in The Lancet suggest that simvastatin, a cheap cholesterol lowering drug, might be a potential
treatment option
for the secondary progressive, or chronic, stage
of multiple sclerosis (MS), which is currently untreatable.
«As
treatments for the earliest stages
of AMD are developed in the coming years, correct identification
of AMD in primary eye care will be critical
for routing patients to
treatment as soon as possible so that the disease can be treated in its earliest
phases and central vision loss avoided.»
With approximately two - thirds
of responders to AF - 219
treatment showing more than a 50 % reduction in cough frequency, we plan to advance the development
of AF - 219 by initiating a
Phase 2b study in patients with chronic cough early next year and to initiate other studies in preparation
for registration studies.»
The
Phase 2/3 trials will be sponsored by Vtesse, a new biotech company that was formed specifically to evaluate the safety and efficacy
of cyclodextrin
for the
treatment of NPC and ultimately obtain FDA labeling if the drug is effective.
A third cannabinoid, cannabidiol, is currently in
phase 3 trials
for treatment of seizures.
In a small
phase I and II clinical trial, Johns Hopkins researchers and colleagues elsewhere found that the high - fat, low - carbohydrate ketogenic diet was a safe and effective
treatment option
for the majority
of adults experiencing a relatively rare, often fatal and always severe form
of epilepsy marked by prolonged seizures that require medically induced comas to prevent them from further damaging the body and the brain.
A $ 2.4 million, 12 - week
phase 1 trial testing the safety and tolerability
of the steroid allopregnanolone
for treatment of mild cognitive impairment and Alzheimer's, led by Roberta Brinton and Lon Schneider
of the University
of Southern California in Los Angeles.
«The percentage
of patients who benefited from
treatment with hu14.18 K322A was unusual
for a
Phase I study.»
Tony Wyss - Coray
of Alkahest has had to scrap the placebo group
for the safety
phase of a trial
of young blood plasma as a
treatment for Alzheimer's because
of a lack
of recruits.
Researchers at Massachusetts Eye and Ear / Harvard Medical School and the University
of Crete have conducted a
phase I / II clinical trial investigating the efficacy
of statins (cholesterol - lowering medications)
for the
treatment of patients with the dry form
of age - related macular degeneration (AMD)-- the leading cause
of blindness in the developed world.
The results
of two
phase 3 clinical trials that led to FDA approval
of adalimumab
for treatment of the chronic inflammatory skin disease hidradenitis suppurtiva (HS) are being published in the August 4 New England Journal
of Medicine.
«Five - year survival data: Brentuximab vedotin may be curative in some with Hodgkin lymphoma:
Phase II trial suggests therapy should be standard
of care
for patients facing relapsed or
treatment - resistant Hodgkin lymphoma.»
«Autologous stem cell transplant should be standard care
for HIV - associated lymphoma: Multicenter,
Phase II trial suggests autologous transplant should be standard
of care
for HIV patients with relapsed /
treatment - resistant lymphoma.»
Guselkumab, a fully human monoclonal antibody targeting IL - 23, in this
Phase 2 study
for the
treatment of PsA, was well tolerated with no unexpected safety findings in this patient population.2 Guselkumab is now being pursued in a
Phase 3 development programme
for psoriatic arthritis.
In the meantime, Fologea completed the initial
phase of another method to provide similar results by using only materials previously approved by the FDA
for treatment of cancer and other diseases.
Abadir and colleagues first tested 5 percent topical losartan on mice in three different
phases of wound healing: group 1
treatment,
for up to three days post-wound infliction to target the inflammatory
phase; group 2
treatment, starting on day seven after wound infliction to target the proliferative / remodeling (later)
phase of tissue healing; and group 3
treatment, starting the first day
of wound infliction until closure to treat all wound healing
phases.
P - BCMA - 101 is Poseida's lead CAR - T therapy currently in
Phase 1 clinical development
for the
treatment of multiple myeloma.