In essence, this re-capitulated the tumor outgrowth
phenotype observed for the parental d42m1 tumor.
Not exact matches
The accepted scientific explanation
for this similarity is that exons are critical regions
for the viability of an organism and therefore many mutations lead to lethal
phenotypes and are therefore not
observed.
Aneuploidy is responsible
for the
observed phenotypic changes, as chromosome loss restoring euploidy results in a wild - type
phenotype.
While similar
phenotypes observed in bsl1 have been described
for d11 mutants in rice (e.g., semidwarf stature, small seeds, and clustered panicle branches; Tanabe et al., 2005; Wu et al., 2016), the lack of bristles is a
phenotype unique to S. viridis.
Furthermore, we found that the stem - like and EMT
phenotypes observed in the cycling hypoxia - selected subpopulation are not reversible, because we obtained the same molecular profile from this subpopulation by culturing them as spherical cultures
for several months in normal oxygen content and culturing them as adherent cells (Figure S2 in Additional file 2).
Students can perform RNAi «from scratch» using bioinformatics to develop PCR primers
for a target gene, then cloning the amplified product into an RNAi feeding vector, and finally
observing the
phenotype of treated worms.
«Exploitation of the same habitat, but key differences at important times of the year, suggests that competition between a single species works to preserve the different
phenotypes we
observed - whilst simultaneously creating the potential
for so - called sympatric speciation, i.e. the potential
for a new species to form without geographic isolation,» says Hawley.
(11) To test
for possible developmental compensation
for more subtle Wnt defects, they examined haploinsufficient crosses of CAST / EiJ mTERT + / — mice; none of the multiple defects
observed in mice with knockouts of multiple different Wnt subtypes; again, no such
phenotypes were
observed.
A unique processed MSP1 intermediate was identified in LLM but not
observed in WT suggesting that delayed processing may be important
for the
observed phenotype.
This is a case with multiple chromosomal aberrations which are likely etiological
for the
observed psychiatric
phenotype consisting of attention deficit hyperactivity and conduct disorders.