Sentences with phrase «phenotypic expression»
"Phenotypic expression" refers to how an organism's genetic traits are visibly shown or displayed in its physical appearance or behavior. It is the observable or measurable characteristics of an organism that are a result of the interaction between its genetic makeup and environmental factors. Full definition
Variation in genetic background may alter expression of the disease allele in affected animals, thus accounting for variation in phenotypic expression of the disease.
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These so - called endophenotypes represent intermediate, subclinical - phased transitions toward a fully manifest phenotypic expression of a disease or disorder (John and Lewis 1966; Gottesman and Gould 2003).
In this paper, we focus on the latter limitation, viewing it as a reflection both of the different clinical presentations of many diseases (variable phenotypic expression), and of the excessive reliance on Cartesian reductionism in establishing diagnoses.
Prevailing theory was that these do not contribute to phenotypic expression and therefore are unimportant.
Online Mendelian Inheritance in Man (OMIM ®) is a continuously updated catalog of human genes and genetic disorders and traits, with particular focus on the molecular relationship between genetic variation and phenotypic expression.
There are multiple environmental factors such as caloric intake, level of exercise, and weather that can affect the severity of clinical signs and phenotypic expression (radiographic changes).
The role of inheritance in behavior was reviewed by Plomin (Science 248:183 - 188, 1990), who pointed out that the genetic influence on behavioral disorders rarely accounts for more than half of the phenotypic expression of behavioral differences.
Dostal J, Hrdlicova A, Horak P. Progressive rod - cone degeneration (PRCD) in selected dog breeds and variability in its phenotypic expression.
According to Sue DeNise, vice-president of MMI Genomics, creators the Canine Heritage Breed Test for mixed breed dogs, each test result is furnished to the dog owner with the following proviso: «Your dog's visual appearance may vary from the listed breed (s) due to the inherent randomness of phenotypic expression in every individual.»