Sentences with phrase «phenotypic profiling»

Mass Cytometry is a next - generation flow cytometry technology that enables highly dimensional functional and phenotypic profiling of single cells within heterogeneous populations.

SKAnking with Ska3: essential role of Ska3 in cell division revealed by combined phenotypic profiling.

Through systematic annotation of the resulting movies, we developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling us to predict new functions for previously uncharacterized genes.

Perform phenotypic profiling in primary human cells to identify and characterize candidate genes with therapeutic potential,

This allows for the combination of many more antibodies (over 30) for phenotypic profiling and functional analysis of single cells, without significant overlap between channels.

Such targets have recently been discovered in cell lines derived from aggressive childhood tumors using phenotypic profiling and RNAi screening.

Melanoma - prone families with CDK4 germline mutation: Phenotypic profile and associations with MC1R variants

OBJECTIVE The purpose of the study was to investigate the combined impact of hormone replacement therapy (HRT) and active lifestyle on the phenotypic profile and in vitro activities of specific

Not exact matches

One of these, his most influential, outlines his original use of microarray expression profiles as a phenotypic footprint for gene function.

The approach to target validation utilizes RNAi, CRISPR, and ORF expression platforms to genetically perturb candidate target gene expression in relevant cancer cell lines, and then profile the resulting phenotypic changes with regard to their effect on various biochemical pathways.

This involves a large and growing number of teams and projects working towards a federated platform (Exchange) to facilitate the matching of cases with similar phenotypic and genotypic profiles (matchmaking) through standardized application programming interfaces (APIs) and procedural conventions.

The isolates were selected on the basis of diversity of phenotypic resistance profiles and clinical source of isolation (blood, CSF and rectal swab).

Phenotypic performances profile of children with reading disabilities: A regression - based test of the phonological - core variable - difference model

The phenotypic test to identify affected dogs is thyroglobulin autoantibodies (TgAA).1 Based on thyroid profiles run at the Michigan State University DCPAH, 10.7 % of 55,053 mixed breed dogs tested affected for autoimmune thyroiditis.