Sentences with word «phorbol»

In normal intact cells, activation of protein kinase C (PKC) by phorbol ester either stimulated or inhibited chloride secretion, depending on the physiological status of the cell.

Cells were restimulated for 5 hr in the presence of BFA with or without 5 μg / ml phorbol 12 - myristate 13 - acetate (PMA)(Sigma), 0.5 μg / ml ionomycin (Sigma) and 50 ng / ml IL - 23.

It is worth noting that «academic drugs» need not be blockbusters and that most life sciences rely heavily on small - molecule effectors (e.g., A23187, phalloidin, or phorbol ester).

Transcription of Gasp was not affected upon stimulation with phorbol 12 - myristate 13 - acetate (PMA) and ionomycin.

Methods: For their studies, the team used PMA (phorbol 12 - myristate 13 - acetate)-- a secretagogue (a substance that causes secretion of another substance) and tumor promoter — to stimulate protein release from HMEC.

Members of the vanilloid receptor family (TRPV) are activated by a diverse range of stimuli, including heat, protons, lipids, phorbols, phosphorylation, changes in extracellular osmolarity and / or pressure, and depletion of intracellular Ca2 + stores.