Not exact matches
is the birthday of Gertrude Perlmann, a pioneer in the chemistry of
proteins, particularly
phosphoproteins.
Corticosterone increases the amount of
protein 1, a neuron - specific
phosphoprotein, in rat hippocampus
Dopamine and adenosine 3 ′, 5 ′ - monophosphate — regulated
phosphoprotein (32 kilodaltons)(DARPP - 32), which is enriched in all neurons that receive a dopaminergic input, is converted in response to dopamine into a potent
protein phosphatase inhibitor.
Two - dimensional polyacrylamide gel electrophoresis combined with chromatographic
phosphoprotein pre-enrichment and electrospray ionization mass spectrometry - based
protein identification was used to reveal changes of
phosphoproteins in cells exposed to cyclic stretching.
Here, we provide evidence that mTOR signaling
phosphoproteins, including mTOR, eukaryotic initiation factor 4E — binding
protein - 1, p70S6K, and ribosomal
protein S6, are highly phosphorylated in ALK + ALCL cell lines and tumors.
An additional 149 candidate
phosphoproteins were identified by profiling the composition of the
protein immobilized metal affinity chromatography enrichment.
These represent 79
proteins, half of which are novel
phosphoproteins, and include several highly phosphorylated
proteins such as MAP1B (33 sites) and Bassoon (30 sites).