Sentences with word «photolyase»

This is possible thanks to an enzyme called DNA photolyase, which is so specialised that cryptochrome, a structurally similar molecule, is unable to do the same job.

Blaustein and Hays already knew that UV radiation damages DNA, and that an enzyme called photolyase can repair this damage.

This is due to electrostatic interactions between the positive charges on the protein surface of photolyase and the negatively charged backbone of the DNA.

Their results, says Krutmann, suggest that «a combination of conventional sunscreens with photolyase could significantly improve sun protection.»

Stada, a German company, sells sunscreen and lotion in Europe containing photolyase, an enzyme that fixes certain DNA errors that can lead to mutations.

So dermatologist Jean Krutmann of the Heinrich Heine University in Düsseldorf, Germany, and his colleagues wondered whether a lotion containing algal photolyase could repair sunburnt DNA in humans.

Plants and some animals have naturally - occurring photolyase in their systems, although humans and other mammals do not.

It all comes down to some new understandings about an enzyme named photolyase.

In organisms lucky enough to possess photolyase, the enzyme rips open the dimer in two places, restoring the DNA molecule to its unharmed state.

Now that Zhong and his Ohio State colleagues better understand the DNA - repairing process, they are hoping that synthetic photolyase could be produced, and incorporated into drugs or lotions for use on human sunburn victims.

The authors found that the binding energy between (6 - 4) DNA photolyase and DNA is much lower than that between cryptochrome and DNA.

They measured levels of the enzyme in the eggs of 10 species, and found that disappearing species have much lower levels of photolyase than healthy ones.

This enzyme, called photolyase, finds and corrects pyrimidine dimers, an abnormal linkage between two neighboring DNA building blocks.

In a 2000 study, researchers showed that a photolyase lotion reduces the number of such errors in the skin, although no tests have yet been conducted to show it reduces the incidence of skin cancer.

The first is an enzyme specialised in DNA repair, called (6 - 4) DNA photolyase, and the other is cryptochrome, which is very close to photolyase structurally but has a completely different biological function and is unable to recognise damage to DNA.

The team irradiated skin patches of 19 volunteers with a UV lamp, then treated some of them with a photolyase lotion and took tiny skin samples.

The study suggests that the photolyase lotion could work like a «morning - after pill» for sun - worshippers, he adds.

This is because the one electron that is ejected from the photolyase first causes a break in the chemical bond on the near side of the dimer, but then travels around its outer edge to cause the second break.