Sentences with phrase «photoreceptor cell death»

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

Not exact matches

They were able to follow the activity of the immune cells using time - lapse 3 - D microscopy imaging of fish retinas and found that neutrophils, the type of immune cells that are typically the first responders to tissue injury, were largely unresponsive to photoreceptor death.

«This is important because the death of photoreceptor cells is known to cause retinal degenerative diseases in humans that lead to blindness.

The researchers injured the mice retinas with a toxin that causes cell death in retinal ganglion cells and interneurons, another type of retinal cell whose job it is to transmit signals from photoreceptors to the brain.

But what scientists did not know is how the mutations trigger a molecular signaling pathway that leads to the death of photoreceptor cells.

«But in this case, the photoreceptor cells are fine in the beginning, so the death of the photoreceptor cells is a secondary affair that is somehow driven by the deficiency in horizontal cells,» he says.

All of these diseases involve the death of photoreceptor cells and each is caused by a distinct genetic mutation.

AMD, a major cause of irreversible vision loss in the elderly, results from death of cells critical for vision: RPE and photoreceptor cells.

It results from the death of cells critical for vision: retinal pigment epithelial cells (RPE) and photoreceptor cells.

These retinal cells are the type that are killed off in macular degeneration, eventually leading to the death of photoreceptors, and the gradual loss of central vision.