This implant makes use of bipolar cells, as these form the second layer downstream of
photoreceptor cells lost to the progress of disease.
Not exact matches
The downside is that people with these eye diseases are
losing sight in large part because they're
losing a different type of eye
cell: the
photoreceptors that sense light in the retina.
In people with RP and AMD, the
photoreceptors have been damaged and
lost, so the ganglion
cells do not receive signals and the brain can not produce an image.
There are even efforts underway to transplant cultured
photoreceptor cells into the retina to replace those
lost from advanced disease.
If the layer is not sustained, which the implant intends to replace, then the
photoreceptor cells also die off, and people
lose their sight slowly as a result.
In the past, neural stem and progenitor
cells from various sources were introduced into eyes with the thought that they might differentiate and replace
photoreceptors lost in retinal disease [13]--[19].
In RCD3 affected dogs normal rod - mediated ERG responses fail to develop,
photoreceptor outer segments do not reach maturity and rod
cells are
lost by apoptosis [5].