Sentences with phrase «photoreceptor material»

Importantly, akin to HESC - RPE in vivo, cells at the outside edge of the iPS - RPE cell bolus could phagocytose photoreceptor outer segments from the RCS rat, as indicated by the presence of rhodopsin - positive photoreceptor material within the cellular membrane of iPS - RPE labelled with HSM (Fig. 5E).

iPS - RPE are capable of phagocytosing photoreceptor material, in vitro and in vivo following transplantation into the Royal College of Surgeons (RCS) dystrophic rat.

The location of transplanted human cells, their expression profile and ability to phagocytose rod photoreceptor material was examined in vivo using immunohistochemistry.

Not exact matches

Stout notes that in order to make it to the next steps, color - blindness research will have to demonstrate that the treatment consistently targets the proper photoreceptor cells and that both the virus and the genetic material are safe.

We aim to develop an artificial photoreceptor based on photovoltaic organic materials for future retinal prosthetic devices.

Phagocytosis of photoreceptor outer segments was defined by the inclusion of rhodopsin - labelled material within the TRA -1-85-bordered intracellular compartment of grafted human iPS - RPE cells.

However, based on the available data, the presence of autofluorescent material does not provide us with specific clues about the cellular and molecular disease mechanisms resulting in photoreceptor loss and retinal degeneration.

(D) Accumulation of autofluorescent material (green) within the RPE can also be seen in a well preserved region of a 13 - year old Stage - 2 affected retina (arrow), possibly indicating that increased autofluorescence may precede loss of photoreceptors.

Because this material appears to be more abundant in affected Swedish vallhund dogs compared to other forms of PRA with primary photoreceptor death or compared to the normal aging canine retinas, we suspect that the autofluorescent material is intimately associated with the disease - causing gene mutation.

(C) At the transition between relatively well preserved and completely absent (*) retinal architecture, loss of photoreceptors (cones are labeled red with hCAR antibody) is associated with accumulation of autofluorescent material (green) in the subretinal space and within the RPE (arrows).