Sentences with phrase «photoreceptor proteins»

«In our research, we were able to create an entirely recombinant protein - based light - sensitive hydrogels by covalently assembling the CarHC photoreceptor proteins using genetically encoded SpyTag - SpyCatcher chemistry,» said Fei Sun, author of the paper and assistant professor at HKUST's department of chemical and biomolecular engineering.

In a report published online this week by Science, Deng and his colleagues suggest that in the plant Arabidopsis thaliana, blue - light photoreceptor proteins known as cryptochromes cozy up to COP1.

Unlike typical bird photoreceptor proteins that change shape when they absorb light energy, cryptochrome generates free electrons when it absorbs light.

They use the photoreceptor protein phytochrome B to see light and then regulate processes such as seed germination, seedling development, longitudinal growth and flower formation.

Cord1 - PRA is a genetic disorder associated with a recessive mutation in the RPGRIP1 gene, which codes for an important photoreceptor protein in the eye.

Not exact matches

Many of the neurons took up the foreign instructions, synthesized ChR2 protein and inserted the photoreceptors in their membrane.

They might also come up with a way to select the right cells out of a mixed population; Anand Swaroop, an ophthalmology researcher at the University of Michigan at Ann Arbor, is working on a way to identify and weed out the photoreceptor cells by focusing on proteins present on cell surfaces.

A good example of compartmentalization is observed in a specialized type of light - sensing neurons found in the retina, the photoreceptors, which are made up of different compartments containing specific proteins essential for vision.

Although researchers knew that CONSTANS production levels varied, the new study shows that the protein is subject to «a whole other level of regulation... that's controlled by these photoreceptors,» says molecular biologist Mark Doyle of the University of Wisconsin, Madison.

The patients had malfunctioning RPE65 genes, which code for a protein that ensures the photoreceptor cells in the retina work smoothly.

«This is the first time that such an integral membrane protein has been localized in the photoreceptor cells and shown to have the capacity to support sight,» notes Dr. Bazan, the paper's corresponding author.

In the future, ultrafast laser crystallography promises to illuminate a broad range of biomolecules, from light sensitive photoreceptors to other vital proteins.

Featured on the cover of Developmental Cell, a paper by OIST researchers revealed the mechanistic link between photoreceptor cell degeneration and defects in protein transport.

An additional surprise was that the differentially expressed proteins were present not only in photoreceptor cells but also in other cells in the retina, including horizontal and Müller cells.

Lack of protein - tyrosine sulfation disrupts photoreceptor outer segment morphogenesis, retinal function and retinal anatomy.

Interphotoreceptor retinoid - binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments.

Human ES cells treated with Noggin, Dickkopf - 1, and Insulin - like Growth Factor - 1 proteins differentiate into functional photoreceptors [5].

Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins.

Confocal images of P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).

A population of these cells forms a layer deep to the photoreceptors, where they contain intracellular pigment granules and appear superficially like an extra RPE layer, even though they do not express at least two characteristic RPE proteins.

I became an eye researcher completely by accident while trying to unravel the role of a protein called Ankyrin in forming biological important membrane domains in cells, in this case, the photoreceptor.

Using the Mfrprd6 model, and others with similar protein localization and phenotypes when mutated, we hope to gain a better understanding of how RPE cells affect photoreceptor development and the process of phagocytosis.

First, it serves to phagocytize and degrade proteins and lipids shed by photoreceptor OS discs, and second, it recycles the vitamin A chromophore necessary for the phototransduction cascade.

Light perception takes place in the cone and rod photoreceptor cells of the retina, a structure at the back of the eye, through a set of proteins denominated phototransduction cascade proteins.

ERG abnormalities are evident by 5 — 6 weeks of age and cell degeneration is present by 4 months, suggesting the mutant protein has a toxic gain of function that severely compromises the early stage of development of the photoreceptors.

Immunohistochemically, CCDC66 protein is detected mainly in the inner segments of photoreceptors in mouse, dog, and man although the retinas of affected Schapendoes have been shown to lack CCDC66 protein [28].

The photoreceptors of dogs that carry this mutation develop normally, in contrast to those of dogs with XLPRA2, and remain morphologically and functionally normal until young adulthood, indicating the C - terminal of the RPGR protein is not essential for functional and structural differentiation of rods and cones.

To further examine the morphology of cells and the localization of protein expression within the retina, immunohistochemical staining of both paraffin and OCT retinal sections was performed with the following antibodies (Table S1): human cone arrestin (for cone photoreceptors), rhodopsin (for rod photoreceptors), RPE65 (for the retinal pigment epithelium, RPE), glial fibrillary acidic protein (GFAP, for astrocytes and Müller cells), glutamine synthetase (for Müller cells) and G0alpha (for ON bipolar cells).