Sentences with phrase «photoreceptors do»

«When horizontal cells are blocked from being formed — the immediate consequence of knocking out Onecut1 — the photoreceptors don't get what they need to survive, so they degenerate and die later on.»

But he points out that as most of the experiments were done under monochromatic light, it's difficult to predict what the full suite of photoreceptors do in natural daylight.

Not exact matches

It took nearly eight decades for scientists to investigate his claim and prove him right: The eye really does contain a third type of photoreceptor cells that sense light intensity without detecting images.

Some groups, including Lanza's, are looking to do just that: transplant photoreceptor cells.

They demonstrated that not only does NPD1 protect photoreceptors, but it also promotes remarkable neurological recovery from the most frequent form of stroke in humans.

When mice ate chow containing tamoxifen (about six to eight times the dose usually given to humans), the microglia didn't overreact and the photoreceptors were spared, the researchers found.

In people with RP and AMD, the photoreceptors have been damaged and lost, so the ganglion cells do not receive signals and the brain can not produce an image.

«We know that other animals use polarisation patterns in the sky, and we have at least some idea how they do it: bees have specially - adapted photoreceptors in their eyes, and birds, fish, amphibians and reptiles all have cone cell structures in their eyes which may help them to detect polarisation,» says Dr Richard Holland of Queen's University Belfast, co-author of the study.

If a new kind of photoreceptor appeared in the retina but the brain didn't process anything differently, «how could that new mutation get propagated through the population?»

Most people who have lost vision due to hereditary retinal degeneration have either no photoreceptors with which to perceive light or photoreceptors that don't work.

But what scientists did not know is how the mutations trigger a molecular signaling pathway that leads to the death of photoreceptor cells.

«We didn't think that they'd be involved in photoreceptor cell degradation.

A population of these cells forms a layer deep to the photoreceptors, where they contain intracellular pigment granules and appear superficially like an extra RPE layer, even though they do not express at least two characteristic RPE proteins.

The Argus II's 60 electrodes are trying to do the job of the eye's roughly 125 million photoreceptor cells, so it's not surprising that they produce extremely crude images.

Of note, while vision rescue requires preservation of some functional photoreceptors, the mere presence of photoreceptor cells in the ONL of transplanted RCS rats does not assure function [61].

By wirelessly stimulating these photoreceptors, which are able to sense light even though they don't generate vision, scientists can better understand their role in regulating physiological functions such as circadian rhythm, sleep and melatonin secretion.

The team performed the same transplantation experiments in immature pre-wean B6J pups and obtained similar results, indicating that the maturity of the recipient retinal environment does not affect photoreceptor precursor integration.

In RCD3 affected dogs normal rod - mediated ERG responses fail to develop, photoreceptor outer segments do not reach maturity and rod cells are lost by apoptosis [5].

However, based on the available data, the presence of autofluorescent material does not provide us with specific clues about the cellular and molecular disease mechanisms resulting in photoreceptor loss and retinal degeneration.