Sentences with word «photosensitizer»

Functional imaging of photosensitizers using multiphoton microscopy.

These schematic drawings show how researchers applied laser pulses to HCN channels tagged with a fluorescent photosensitizer to observe the effects on these channels of singlet oxygen, a highly reactive form of oxygen that plays a role in a range of biological processes including photosynthesis and skin cancer / aging.

The path to clinical use could be short, he suggests, because I124 - chlor is based on a FDA - approved photosensitizer developed at Roswell Park, and the new technique employs widely available PET and endoscopic technology.

In the resulting composite, both the black phosphorous and gold nanoparticles work as photosensitizers, the former responding to visible and near - infrared light, and the latter responding to visible light.

Bergamot contains bergaptene, a dominant photosensitizer, and can cause severe reactions.

In April 2000, the U.S. Food and Drug Administration (FDA) approved the production of Visudyne, a QTL - produced photosensitizer used in the treatment of macular degeneration.

Although much progress has been made in recent years in the development of catalysts devoid of noble metals, photosensitizers still rely, in the main, on molecular compounds containing rare and costly metals, such as ruthenium and iridium, or on inorganic semiconductor materials containing cadmium, a toxic metal.

This system's performance is much higher than that obtained with a ruthenium - based photosensitizer, due to the very high stability of inorganic quantum dots, which can be recycled several times without notable loss of activity.

Uroporphyrinogen I is a reduced porphyrin that can undergo spontaneous oxidation to form the potent photosensitizer uroporphyrin I. Intense light exposure causes porphyrin molecules to generate reactive oxygen species (ROS).

By applying millisecond laser light pulses to HCN channels tagged with a fluorescent photosensitizer, Zhou and colleagues were able to elicit the production of small amounts of singlet oxygen in a precise location and monitor its effects on the channels in open and closed states.

In artificial photosynthesis systems chromophores, or «photosensitizers,» absorb light energy and transfer electrons to the catalyst, which activates the chemical reaction.

Svenskaya, Y., Parakhonskiy, B., Haase, A., Atkin, V., Lukyanets, E., Gorin, D. & Antolini, R. (2013), Anticancer drug delivery system based on calcium carbonate particles loaded with a photosensitizer.

During her undergraduate studies, Stacey worked in the laboratory of Dr. Anirban Sen Gupta to develop a polymeric micelle formulation of a photosensitizer for photodynamic therapy of cancer.

PCI, on the other hand, allows for targeted disruption of the barrier by combining light activated drugs, or photosensitizers, with drugs known to disrupt the blood - brain barrier.

Then, a specific wavelength of light therapy is focused on the target area, activating the photosensitizers and releasing the barrier - busting molecules.

Researchers note that while PCI - aided delivery of chemotherapy to the brain has proven effective in laboratory tests, additional testing prior to human clinical trials is needed to identify other less - toxic blood - brain barrier agents to be used in tandem with the photosensitizer in the PCI process.

In PCI, photosensitizers are injected into the patient.

The photosensitizers surround the drug molecules and prevent them from infiltrating the entire brain.

One of the concerns with this one is that like octinoxate, it acts as a photosensitizer, actually increasing the production of free radicals when skin is exposed to the sun.

Fragrances can be skin allergens, irritants, and photosensitizers 1 - 2 % of the population may have an allergy to fragrances.

She developed a photosensitizer for photodynamic therapy, using light energy to activate a drug that kills cancer cells.