Phthalates are considered endocrine disrupters, and studies have shown a statistical association between
phthalate exposure and male sexual development.
However, the contribution of dietary intake to
phthalate exposure has not been well defined.»
So, what foods should pregnant women stay away from to decrease
their phthalate exposure in hopes of avoiding the phthalate - related syndrome of incomplete virilization?
What's the problem with
phthalate exposure?
This research was the 1st to look at the connection between
phthalate exposure and measurements made use of to determine childhood obesity.
There is also now abundant research that links BPA and
phthalate exposure to such human health concerns as deformities of the male and female genitals; premature puberty in females; decreased sperm quality; and increases in breast and prostate cancers, infertility, miscarriages, obesity, type 2 diabetes, allergies and neurological problems, like attention deficit hyperactivity disorder.
In one 2014 study, which Barrett co-authored,
phthalate exposure late in pregnancy was associated with behavioral problems in boys who were six to 10 years old.
[23] Because phthalates can cross the placenta and are present in and can be transmitted though breast milk, [24] it is important that women of child - bearing age, pregnant women and mothers who are breast - feeding avoid
phthalate exposure.
Food packaging and bisphenol A and bis (2 - ethyhexyl)
phthalate exposure: findings from a dietary intervention.
Phthalate exposure in girls during early puberty.
This study also investigated peripubertal BPA and
phthalate exposure, which was related to higher leptin in boys.
Phthalate exposure is linked to early puberty in girls, a risk factor for later - life breast cancer.
Check out our interview with Dr. Zota on her recent study, which tracked levels of
phthalate exposure in people:
«We found evidence reduced levels of circulating testosterone were associated with increased
phthalate exposure in several key populations, including boys ages 6 - 12, and men and women ages 40 - 60,» said one of the study's authors, John D. Meeker, MS, ScD, of the University of Michigan School of Public Health in Ann Arbor, MI.
«Our study is the first to show that hCG is a target of
phthalate exposure in early pregnancy and to confirm previous findings that it is a critical hormone in male development,» Adibi said.
Researchers found evidence of reduced levels of circulating testosterone with increased
phthalate exposure.
Researchers found an inverse relationship between
phthalate exposure and testosterone levels at various life stages.
The cross-sectional study examined
phthalate exposure and testosterone levels in 2,208 people who participated in the U.S. National Health and Nutrition Examination Survey, 2011 - 2012.
The authors believe theirs is among the first human studies to investigate the influence of
phthalate exposure on sperm epigenetics, embryo development and whether DNA methylation in sperm cells may be a path by which a father's environmental exposure influences these endpoints.
Phthalate exposure, known to disrupt endocrines, is associated in human studies with changes in semen quality, androgen levels, birth outcomes and offspring neurodevelopment, but a mechanism has not been clearly identified, Pilsner says.
«Dad's
phthalate exposure, reproductive success.»
Pilsner and colleagues will examine the possible influence of paternal
phthalate exposure on sperm quality and embryo development and whether DNA methylation in sperm cells may be a pathway by which a father's exposure influences these endpoints.
Phthalate exposure does not come just from moms.
To see if
phthalate exposure might influence this developmental period, Skakkebaek and his colleagues investigated how the amount of phthalates in breast milk correlated with a baby's hormonal profile.
Some studies suggest that
the phthalate exposure most people get from phthalate - containing products is lower than the doses shown to be harmful in animals.
The first study to look at prenatal
phthalate exposure and later effects on respiration suggest some worrisome results
A study of New York City students found that
phthalate exposure was linked to behavioral problems
We found a strong association between several phthalates and infant care products that are applied dermally and therefore conclude that this is a major source and route of exposure for infant
phthalate exposure, but phthalates from these products may also be ingested orally and inhaled.
«Prenatal
phthalate exposures and anogenital distance in swedish boys.»
Furthermore, available evidence from in vitro studies suggests that one of the possible mechanisms through which
phthalates exposure may affect insulin sensitivity is oxidative stress, either by activation of peroxisome proliferator — activated receptors (20) or by changes in mitochondrial membranes potential and permeability (21).
Not exact matches
«Dining out associated with increased
exposure to harmful chemicals: New study finds burgers and other foods consumed at restaurants, fast food outlets or cafeterias, associated with higher levels of
phthalates.»
In an effort to limit my family's
exposure to BPA and
phthalates, I've tossed all those freebie plastic water bottles and replaced them with aluminum Sigg bottles.
Filed Under: A Green Home Tagged With: Animal Studies, Baby Boys, baby toy, Centers For Disease Control, Centers For Disease Control And Prevention, Centers For Disease Control And Prevention Cdc, Dbp, Dibutyl
Phthalate, Disease Control And Prevention, Environmental Health Perspectives, Flooring Adhesives, Human
Exposure, Immune Suppression, Organ Damage, Personal Care Products,
Phthalate,
phthalates, Reproductive Health, Reproductive Organ, Reproductive Organs, Shower Curtains, Toys, Wood Finishes
Since this month's publication in the medical journal Pediatrics of a study linking infant
exposure to shampoos, powders and lotions with increased urinary concentrations of
phthalates, many parents have been replacing their favorite baby brands with organic alternatives.
Flynn goes further than most by telling women they can reduce BPA
exposure by not buying canned foods and beverages with resin liners, and that they can avoid cosmetics and plastics containing chemicals called
phthalates.
Davis can't say why the shift is occurring, but she suspects the cause is
exposure to estrogen - mimicking chemicals in the environment: so - called metalloestrogens like arsenic and mercury, as well as pesticides, solvents, plastics, including
phthalates (see story # 42, page 46), and PCBs.
«At least a dozen studies have shown the effects of
phthalates on human reproduction,» says University of Rochester epidemiologist and biostatistician Shanna Swan, the lead author of a much - cited study that showed higher
exposure to some
phthalates in mothers correlates with reduced «anogenital distance» in newborn boys.
They identified 6,479 regions of interest in assessing a possible correlation between
phthalate metabolite
exposure and DNA methylation.
Pilsner hypothesizes that
exposure to certain plastics such as
phthalates and other chemicals during this reprogramming event is associated with changes in methylated tags on the sperm's DNA.
But it's unclear what health outcomes, if any, can be attributed to high
exposures to
phthalates during infancy.
Shanna Swan, director of the University of Rochester's Center for Reproductive Epidemiology, conducted studies that found an association between pregnant women's
exposure to
phthalates and altered genital development in their baby boys.
The report noted that the high
exposure of premature infants in neonatal intensive care units to both BPA and
phthalates is of «great concern.»
The study of 125 babies from the day they were born to 14 months old is the first comprehensive examination of infants»
exposure to several
phthalates.
Phthalates can mimic estrogen or disrupt testosterone, and
exposure of fetuses and infants is the major concern.
In infant boys, prenatal
exposure to dibutyl
phthalate has been linked to feminization of the reproductive tract.
Previous studies have linked
exposure to products containing hormone - disrupting chemicals, such as pesticides and
phthalates, to infertility and poorer reproductive success.
Early
exposure in the human womb to
phthalates, which are common environmental chemicals, disrupts the masculinization of male genitals, according to a new study that will be presented Sunday at the Endocrine Society's 97th annual meeting in San Diego.
«Prenatal
exposure to common chemical,
phthalates, found in some plastics disrupts masculinization of male genitals.»
Among health issues that some advocates have linked to chemical
exposures: early pubescence in girls (BPA hastens the onset of pubescence in juvenile rats); asthma (car and truck exhaust can induce or worsen lung inflammation), and genital malformation (
phthalates have been linked to lower sperm count and deformed penises in rats).
«While the study's cross-sectional design limit the conclusions we can draw, our results support the hypothesis that environmental
exposure to endocrine - disrupting chemicals such as
phthalates could be contributing to the trend of declining testosterone and related disorders,» Meeker said.