Sentences with phrase «physiological genomics approach»

an integrative physiological genomics approach to understand how human populations have adapted to live at high altitude.

Not exact matches

«While previous molecular studies have provided simple snapshots of the gene transcript variations that are associated with the exposure of insects to natural and synthetic chemicals, the genomics approaches used in this study offer a significantly more complex perspective on the biochemical and physiological processes occurring in plant - insect interactions,» Schuler said.

Biomarkers (Rick Paules, Section Editor): This section will present a forum for innovative scientific studies that integrate genomic, proteomic and metabolomic approaches with studies of complex physiological regulatory processes to gain a systems biology insight into complex pathways and networks controlling homeostatic and pathophysiologic states.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.