Sentences with phrase «physiological importance»

We selected seven genes of known physiological importance to the implantation to validate the RNA - seq results; five genes were associated with down - regulation of IFNT signaling in clones on gestation d18 (IFN.tau.c1, IFTN2, CXCL9, CXCL10, and IFI47), and two genes were up - regulated in d - 34 chorion from cloned samples (C3 and IL6).

Surprisingly, none of the three suffers any apparent clinical consequence, which raises questions about the physiological importance of CHIP and implies that other mechanisms may compensate for its absence.

«These discoveries demonstrate a hypothesis that we had made following a basic research study we had just carried out in our laboratory, and thus confirm the physiological importance of the unfolded protein response in the control of neurogenesis,» says Laurent Nguyen.

These results provide evidence in vivo for the physiological importance of β - arrestin 2 in regulating the function of a specific GPCR, the μOR.

Several human and animal investigations have researched the physiological importance of the AR in exercise - induced muscle hypertrophy,1 - 8 emphasizing the importance of exercise at increasing the AR content,1 - 3, 5,6 seemingly in a fiber - specific manner.4

The physiological importance of AR for muscle protein accretion has been demonstrated, as muscle hypertrophy is attenuated by AR blockade.2