Sentences with word «picrotoxin»

40 to 50 min later, ACSF was switched to 0 Mg2 + in the presence of picrotoxin (50 µM) and CNQX (10 µM).

To confirm this, Silva's team gave the NF1 - mutated mice picrotoxin, a drug known to counteract GABA effects.

Temporary relief is sometimes achieved with physostigmine, neostigmine or treatment with picrotoxin.

The pair chemically treated inhibitory neurons by injecting them with droplets of picrotoxin, an antagonist of gamma - aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain.

It's unlikely that picrotoxin can be used in people due to its dangerous side effects, Silva says.

We used a transverse hippocampal slice preparation with two extracellular recording electrodes to capture propagation of compound action potentials (CAPs) elicited by a stimulating electrode in the presence of synaptic transmission blockers (CNQX, APV, and picrotoxin).

mEPSCs were recorded from DA neurons in the presence of picrotoxin (50 µM) and tetrodotoxin (TTX, 1 µM).