Sentences with phrase «pig fibroblast cells»
Researchers used the CRISPR / Cas9 gene editing technique to introduce a segment of a human gene causing Huntington's, with a very long glutamine repeat region, into pig fibroblast cells.
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It takes far more expertise, however, to remove dozens of PERV genes at once, as eGenesis does in pig fibroblasts, which are connective - tissue cells.
To further facilitate genome editing in pigs, we report here establishment of a pig line with Cre - inducible Cas9 expression that allows a variety of ex vivo genome editing in fibroblast cells including single - and multigene modifications, chromosome rearrangements, and efficient in vivo genetic modifications.