This has the potential to initiate a positive feedback loop in which ROS drive further uroporphyrinogen I oxidation, leading to oxidative stress and
pigment cell death.
Not exact matches
Malignant melanoma is the eighth most common cancer in the United States and causes 1 to 2 percent of all cancer
deaths.1, 2 Melanoma is a proliferation of transformed melanocytes or
pigment - producing
cells.
It results from the
death of
cells critical for vision: retinal
pigment epithelial
cells (RPE) and photoreceptor
cells.
In addition, two copies of the M allele large enough to produce the merle coat color are thought to cause the
death of skin melanocytes, retinal
pigment cells, and melanocytes of the inner ear which can result in significant white areas of the coat, eye abnormalities and deafness.
«The lack of
pigment cells causes the
death of the nerve
cells that need to develop for hearing to occur.»
Amy Elkins, Sketch of a
death row
cell interior by a then 23 year old man who has been serving time on
death row for over 13 years, 2010, 11 x 14 inch archival
pigment print.